Prospective memory in non-psychotic first-degree relatives of patients with schizophrenia

被引：19

作者：

Wang, Ya ^{[1
,2
]}

Chan, Raymond C. K. ^{[1
,2
]}

Cui, Jifang ^{[3
]}

Deng, Yongyu ^{[4
]}

Huang, Jia ^{[5
,6
]}

Li, Huijie ^{[1
,2
,7
]}

Yan, Chao ^{[1
,2
,7
]}

Xu, Ting ^{[1
,2
,7
]}

Ma, Zheng ^{[8
]}

Hong, Xiaohong ^{[9
]}

Li, Zhanjiang ^{[8
]}

Shi, Haisong ^{[10
]}

Shum, David ^{[11
,12
]}

机构：

[1] Chinese Acad Sci, Inst Psychol, Neuropsychol & Appl Cognit Neurosci Lab, Beijing 100101, Peoples R China

[2] Chinese Acad Sci, Inst Psychol, Key Lab Mental Hlth, Beijing 100101, Peoples R China

[3] Beijing Normal Univ, Sch Psychol, Beijing 100875, Peoples R China

[4] Guangdong Vocat Coll Mech & Elect Technol, Guangzhou, Guangdong, Peoples R China

[5] Sun Yat Sen Univ, Dept Psychol, Neuropsychol & Appl Cognit Neurosci Lab, Guangzhou 510275, Guangdong, Peoples R China

[6] Sun Yat Sen Univ, Sch Life Sci, Guangzhou 510275, Guangdong, Peoples R China

[7] Chinese Acad Sci, Grad Sch, Beijing 100101, Peoples R China

[8] Capital Med Univ, Beijing Anding Hosp, Beijing, Peoples R China

[9] Shantou Univ, Mental Hlth Ctr, Shantou, Peoples R China

[10] N China Elect Power Univ, Beijing, Peoples R China

[11] Griffith Univ, Sch Psychol, Brisbane, Qld 4111, Australia

[12] Griffith Univ, Griffith Inst Hlth & Med Res, Brisbane, Qld 4111, Australia

来源：

PSYCHIATRY RESEARCH | 2010年 / 179卷 / 03期

关键词：

Schizophrenia; Prospective memory; Non-psychotic; First-degree relative; WORKING-MEMORY; PREFRONTAL CORTEX; ADULT RELATIVES; GENETIC RISK; DEFICITS; IMPAIRMENTS; DYSFUNCTION; PSYCHIATRY; REGIONS; NUMBER;

D O I：

10.1016/j.psychres.2009.07.011

中图分类号：

R749 [精神病学];

学科分类号：

100205 ;

摘要：

Although a number of studies have found prospective memory (PM) impairment in patients with schizophrenia, very little is known about the PM performance in non-psychotic relatives of these patients. The current study aimed to explore the PM performance in non-psychotic first-degree relatives of these patients. Two groups of participants (26 non-psychotic first-degree relatives of schizophrenia patients and 26 healthy comparison participants) were administered three PM tasks (time-, event-, and activity-based) and a set of neurocognitive tests. Results showed that the relatives performed significantly worse than the comparisons on most indices of the PM tasks, with a similar pattern of impairment found in other neurocognitive measures. Together with findings from previous studies, results of the current study suggest that PM may be a potential endophenotype for schizophrenia. (C) 2009 Elsevier Ireland Ltd. All rights reserved.

引用

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页码：285 / 290

页数：6

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