TX-004HR Improves Vaginal Physiology and Dyspareunia with Negligible Systemic Absorption

被引：0

作者：

Constantine, Ginger ^{[3
]}

Pickar, James ^{[1
]}

Archer, David ^{[2
]}

Graham, Shelli ^{[4
]}

Bernick, Brian ^{[4
]}

Mirkin, Sebastian ^{[4
]}

Lobo, Rogerio ^{[1
]}

机构：

[1] Columbia Univ, Dept Obstet & Gynecol, New York, NY USA

[2] Eastern Virginia Med Sch, Dept Obstet & Gynecol, Clin Res Ctr, Norfolk, VA 23501 USA

[3] EndoRheum Consultants LLC, Malvern, PA USA

[4] TherapeuticsMD, Boca Raton, FL USA

来源：

MENOPAUSE-THE JOURNAL OF THE NORTH AMERICAN MENOPAUSE SOCIETY | 2016年 / 23卷 / 12期

关键词：

D O I：

暂无

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

S-6

引用

页码：1371 / 1371

页数：1

共 18 条

[1] TX-004HR vaginal estradiol has negligible to very low systemic absorption of estradiol
Archer, David F.
Constantine, Ginger D.
Simon, James A.
Kushner, Harvey
Mayer, Philip
Bernick, Brian
Graham, Shelli
Mirkin, Sebastian
MENOPAUSE-THE JOURNAL OF THE NORTH AMERICAN MENOPAUSE SOCIETY, 2017, 24 (05): : 510 - 516
[2] A vaginal estradiol softgel capsule, TX-004HR, has negligible to very low systemic absorption of estradiol: Efficacy and pharmacokinetic data review
Simon, James A.
Archer, David F.
Constantine, Ginger D.
Pickar, James H.
Amadio, Julia M.
Bernick, Brian
Graham, Shelli
Mirkin, Sebastian
MATURITAS, 2017, 99 : 51 - 58
[3] Evaluation of Systemic Effects of a Vaginal Estradiol Softgel Capsule (TX-004HR) in Menopausal Women with Moderate-to-Severe Dyspareunia
Larkin, Lisa C.
Kaunitz, Andrew M.
Liu, James
Graham, Shelli
Bernick, Brian
Mirkin, Sebastian
Constantine, Ginger
MENOPAUSE-THE JOURNAL OF THE NORTH AMERICAN MENOPAUSE SOCIETY, 2018, 25 (12): : 1485 - 1485
[4] TX-004HR clinically improves symptoms of vulvar and vaginal atrophy in postmenopausal women
Simon, J. A.
Kagan, R.
Archer, D. F.
Constantine, G. D.
Bernick, B.
Graham, S.
Mirkin, S.
CLIMACTERIC, 2019, 22 (04) : 412 - 418
[5] Significant Improvement in Vaginal Epithelium with TX-004HR in Postmenopausal Women with Moderate-to-Severe Vulvar and Vaginal Atrophy (VVA) and Dyspareunia
Simon, James
Archer, David
Kagan, Risa
Bernick, Brian
Mirkin, Sebastian
MENOPAUSE-THE JOURNAL OF THE NORTH AMERICAN MENOPAUSE SOCIETY, 2016, 23 (12): : 1372 - 1372
[6] REJOICE Trial: TX-004HR Consistently Improved Vaginal Dryness in Subgroups of Postmenopausal Women with Vulvar and Vaginal Atrophy (VVA) and Dyspareunia
Kroll, Robin
Simon, James
Kagan, Risa
Constantine, Ginger
Bernick, Brian
Graham, Shelli
Mirkin, Sebastian
MENOPAUSE-THE JOURNAL OF THE NORTH AMERICAN MENOPAUSE SOCIETY, 2017, 24 (12): : 1444 - 1444
[7] Consistency of Effect with a Low-Dose, Estradiol Vaginal Capsule (TX-004HR): Evaluating Improvement in Vaginal Physiology and Moderate-to-Severe Dyspareunia in Subgroups of Postmenopausal Women
Constantine, Ginger D.
Bouchard, Celine
Pickar, James H.
Archer, David F.
Graham, Shelli
Bernick, Brian
Mirkin, Sebastian
JOURNAL OF WOMENS HEALTH, 2017, 26 (06) : 616 - 623
[8] TX-004HR Improved Moderate-to-Severe Dyspareunia and Vaginal Dryness Associated with Vulvar and Vaginal Atrophy (VVA) in Post-menopausal Women
Kagan, Risa
Minkin, Mary Jane
Graham, Shelli
Bernick, Brian
Mirkin, Sebastian
MENOPAUSE-THE JOURNAL OF THE NORTH AMERICAN MENOPAUSE SOCIETY, 2017, 24 (12): : 1443 - 1443
[9] The Effect of Body Position on the Pharmacokinetics of TX-004HR, Estradiol Vaginal Softgel Capsule
Constantine, Ginger
Mirkin, Sebastian
Bernick, Brian
Graham, Shelli
Pickar, James
Shadiack, Annette M.
MENOPAUSE-THE JOURNAL OF THE NORTH AMERICAN MENOPAUSE SOCIETY, 2016, 23 (12): : 1400 - 1400
[10] A 17β-estradiol, Softgel, Vaginal Capsule (TX-004HR) had an Early Onset of Action for Treating Vulvar and Vaginal Atrophy (VVA) and Moderate-to-Severe Dyspareunia
Constantine, Ginger
Millheiser, Leah S.
Kaunitz, Andrew M.
Graham, Shelli
Bernick, Brian
Mirkin, Sebastian
MENOPAUSE-THE JOURNAL OF THE NORTH AMERICAN MENOPAUSE SOCIETY, 2018, 25 (12): : 1501 - 1501

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