Function of GABAergic and glutamatergic neurons in the stomach

被引：27
|
作者：
Tsai, LH [1 ]
机构：
[1] Taipei Med Univ, Sch Med, Dept Physiol, Taipei 11014, Taiwan
来源：
JOURNAL OF BIOMEDICAL SCIENCE | 2005年 / 12卷 / 02期
关键词：
GABA receptors; GABAergic neuron; glutamate receptors; glutamatergic neuron; stomach;
D O I：
10.1007/s11373-005-1357-0
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
gamma-Aminobutyric acid (GABA) and L-glutamic acid (L-Glu) are transmitters of GABAergic and glutamatergic neurons in the enteric interneurons, targeting excitatory or inhibitory GABA receptors or glutamate receptors that modulate gastric motility and mucosal function. GABAergic and glutamatergic neuron immunoreactivity have been found in cholinergic enteric neurons in the stomach. GABA and L-Glu may also subserve hormonal and paracrine signaling. Disruption in gastrointestinal function following perturbation of enteric GABA receptors and glutamate receptors presents potential new target sites for drug development.
引用
收藏
页码：255 / 266
页数：12
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