COVID-19 and the Incidence of Acute Myocardial Injury

被引：6
|
作者：
Mizera, Lars [1 ]
Borst, Oliver [1 ,2 ]
机构：
[1] Univ Tubingen, Dept Cardiol & Angiol, Tubingen, Germany
[2] DFG Heisenberg Grp Thrombocardiol, Tubingen, Germany
来源：
HAMOSTASEOLOGIE | 2021年 / 41卷 / 05期
关键词：
COVID-19; myocardial infarction; cardiac injury; troponin; II RECEPTOR BLOCKERS; TROPONIN; ADMISSIONS; INFARCTION; MORTALITY; DEATH;
D O I：
10.1055/a-1554-6416
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Cardiovascular manifestations are frequent in COVID-19 infection and are predictive of adverse outcomes. Elevated cardiac biomarkers are common findings in patients with cardiovascular comorbidities and severe COVID-19 infection. Troponin, inflammatory and thrombotic markers may also improve risk prediction in COVID-19. In our comprehensive review, we provide an overview of the incidence, potential mechanisms and outcome of acute cardiac injury in COVID-19. Thereby, we discuss coagulation abnormalities in sepsis and altered immune response as contributing factors favoring myocardial injury. We further highlight the role of endothelial damage in the pathophysiological concepts. Finally, observational studies addressing the incidence of myocardial infarction during COVID-19 pandemic are discussed.
引用
收藏
页码：356 / 364
页数：9
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