Inflammation as a link between periodontal disease and obesity

被引：38

作者：

Pamuk, Ferda ^{[1
,2
]}

Kantarci, Alpdogan ^{[1
]}

机构：

[1] Forsyth Inst, 245 First St, Cambridge, MA 02142 USA

[2] Univ Leuven, KU Leuven, Dept Oral Hlth Sci, Leuven, Belgium

来源：

PERIODONTOLOGY 2000 | 2022年 / 90卷 / 01期

关键词：

inflammation; nutrition; obesity; periodontal disease; TUMOR-NECROSIS-FACTOR; CORONARY-HEART-DISEASE; BODY-MASS INDEX; IMMUNE-MECHANISMS RELEVANT; ENDOTHELIAL GROWTH-FACTOR; VISCERAL ADIPOSE-TISSUE; C-REACTIVE PROTEIN; HUMAN FAT-CELLS; INSULIN-RESISTANCE; FACTOR-ALPHA;

D O I：

10.1111/prd.12457

中图分类号：

R78 [口腔科学];

学科分类号：

1003 ;

摘要：

Nutrition plays a critical role in the homeostatic balance, maintenance of health, and longevity. There is a close link between inflammatory diseases and nutritional health. Obesity is a severe pathological process with grave implications on several organ systems and disease processes, including type 2 diabetes, cardiovascular disease, osteoarthritis, and rheumatoid arthritis. The impact of obesity on periodontal inflammation has not been fully understood; the association between nutritional balance and periodontal inflammation is much less explored. This review is focused on the potential mechanistic links between periodontal diseases and obesity and common inflammatory activity pathways that can be pharmacologically targeted.

引用

页码：186 / 196

页数：11

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