Recent advances in transition-metal-free trifluoromethylation with Togni's reagents

被引：0
|
作者：
Chen, Jin-Yang [1 ]
Huang, Jing [1 ]
Sun, Kai [2 ]
He, Wei-Min [1 ]
机构：
[1] Univ South China, Sch Chem & Chem Engn, Hengyang 421001, Hunan, Peoples R China
[2] Zhengzhou Univ, Coll Chem, Green Catalysis Ctr, Kexue Rd 100, Zhengzhou 450001, Peoples R China
来源：
ORGANIC CHEMISTRY FRONTIERS | 2022年 / 9卷 / 04期
基金：
中国国家自然科学基金; 中国博士后科学基金;
关键词：
MILD ELECTROPHILIC TRIFLUOROMETHYLATION; C-H; RADICAL TRIFLUOROMETHYLATION; ALKENES; CARBOTRIFLUOROMETHYLATION; FUNCTIONALIZATION; ENAMIDES; ALKYNES; AMIDES;
D O I：
10.1039/d1qo01504d
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Transition-metal-free trifluoromethylations have attracted significant research interest driven by the increasing importance of CF3-containing compounds. Among the various trifluoromethylation reagents, Togni's reagents exhibit exceptional reactivities, and many important organic transformations have been realized employing such reagents. This review describes several key activation methods for Togni's reagents under transition-metal-free conditions by showcasing selected cornerstone research areas and related mechanisms to stimulate the interest of readers in participating in the development of novel efficient transition-metal-free trifluoromethylations with Togni's reagents.
引用
收藏
页码：1152 / 1164
页数：13
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