Update on Prognostic Genetic Testing in Adolescent Idiopathic Scoliosis (AIS)

被引：17
|
作者：
Ogilvie, James W. [1 ]
机构：
[1] Axial Biotech Inc, Genet Res Lab, Salt Lake City, UT 84109 USA
来源：
JOURNAL OF PEDIATRIC ORTHOPAEDICS | 2011年 / 31卷
关键词：
genome wide association studies; single nucleotide polymorphisms; adolescent idiopathic scoliosis risk of progression;
D O I：
10.1097/BPO.0b013e3181fd87eb
中图分类号：
R826.8 [整形外科学]; R782.2 [口腔颌面部整形外科学]; R726.2 [小儿整形外科学]; R62 [整形外科学（修复外科学）];
学科分类号：
摘要：
Case-control genome-wide association studies using a large, geographically diverse data base has been used to identify single nucleotide polymorphisms that have prognostic utility in predicting progression of mild adolescent idiopathic scoliosis in White patients. The calculated risk of progression score allows stratification of patients that can make medical care evidence based, less costly, and more efficient.
引用
收藏
页码：S46 / S48
页数：3
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