Early quality of life outcomes after surgery in head and neck cancer survivors with EORTC QLQ-C30 and EORTC QLQ-HN35 in an Asian tertiary centre

被引:2
|
作者
Kao, Nern Hoong [1 ]
Iyer, N. Gopalakrishna [2 ,3 ]
Chua, Alice [4 ]
Nagadia, Rahul Harshad [5 ,6 ,7 ]
机构
[1] Changi Gen Hosp, 2 Simei St 3, Singapore 529889, Singapore
[2] Natl Canc Ctr Singapore, Dept Head & Neck Surg, 11 Hosp Crescent, Singapore 169610, Singapore
[3] Duke NUS Med Sch, 8 Coll Rd, Singapore 169857, Singapore
[4] Singapore Gen Hosp, Outram Rd, Singapore 169608, Singapore
[5] Singapore Gen Hosp, Dept Head & Neck Surg, Outram Rd, Singapore 169608, Singapore
[6] Natl Dent Ctr Singapore, Dept Oral & Maxillofacial Surg, 5 Second Hosp Ave, Singapore 168938, Singapore
[7] Karolinska Inst, Dept Dent Med, S-17177 Stockholm, Sweden
关键词
Head and neck cancer; SCC; Quality of life; QOL; QLQ-C30; QLQ-HN35; Multimodal therapies; QUESTIONNAIRE; THERAPY;
D O I
10.1007/s00520-022-06871-4
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Background The objective of the study was to evaluate the quality of life (QOL) of head and neck cancer survivors after surgical treatment and to identify patients' main concerns. The study also aims to establish pre-treatment reference values particularly for the Asian patient. The European Organization for Research and Treatment of Cancer Quality of Life Questionnaire-Core 30 (EORTC QLQ-C30) and Head and Neck module (EORTC QLQ-HN35) were used for objective evaluation. Methods Patients planned for elective surgery for head and neck cancers were enrolled in the study. The questionnaires were completed at pre-treatment and at 6 months after surgery. Results were compared with previously published reference values. Results One hundred forty patients completed both questionnaires. Locally advanced tumour and extent of surgery (tracheostomy (p<0.01), surgical flap (p<0.01)) were associated with lower global health scores. Adjuvant treatment was also a contributory factor (p<0.01). Dysphagia and social eating was a primary concern within our population. Conclusion Surgical treatment of head and neck cancers is safe, but there is poor QOL in the early post-treatment period especially with eating. Previously published data suggested improvement after a year.
引用
收藏
页码:4537 / 4546
页数:10
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