Low-dose human chorionic gonadotropin versus estradiol/progesterone luteal phase support in gonadotropin-releasing hormone agonist-triggered assisted reproductive technique cycles: understanding a new approach

被引：21
|
作者：
Garcia-Velasco, Juan A. [1 ,2 ]
Motta, Leticia [2 ]
Lopez, Ana [2 ]
Mayoral, Mercedes [2 ]
Cerrillo, Maria [2 ]
Pacheco, Alberto [2 ]
机构：
[1] Rey Juan Carlos Univ, Madrid, Spain
[2] IVI Madrid, Madrid, Spain
来源：
FERTILITY AND STERILITY | 2010年 / 94卷 / 07期
关键词：
hCG; estradiol; progesterone; luteal phase; GnRH agonist; FINAL OOCYTE MATURATION; OVARIAN HYPERSTIMULATION SYNDROME; GNRH AGONIST; LUTEINIZING-HORMONE; OVULATION INDUCTION; ANTAGONIST; HCG; FERTILIZATION; WOMEN; SURGE;
D O I：
10.1016/j.fertnstert.2010.06.035
中图分类号：
R71 [妇产科学];
学科分类号：
100211 ;
摘要：
It remains unclear how GnRH agonist (GnRHa) triggering affects the luteal phase, so we investigated the luteal phase after GnRHa triggering, supported with conventional E-2/P with or without low-dose hCG. E-2/P support, compared with low-dose hCG, induced a shorter luteal phase (11.2 +/- 1.1 vs. 15.0 +/- 1.6 days) and fewer subjective complaints (0 vs. 42%), whereas hCG caused more free fluid accumulation and enlarged ovaries than E-2/P alone. Steroids and low-dose hCG differentially affected corpus luteum function, ovarian size, free fluid accumulation, and patient comfort. (Fertil Steril (R) 2010;94:2820-3. (C) 2010 by American Society for Reproductive Medicine.)
引用
收藏
页码：2820 / 2823
页数：4
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