Synthesis of [15N3]melamine and [13C3]cyanuric acid

被引：4
|
作者：
Luo, Yong [1 ]
Zhang, Liya [1 ]
Yang, Weicheng [1 ]
Liu, Weixia [1 ]
Lu, Weijing [1 ]
Li, Meihua [1 ]
机构：
[1] Shanghai Res Inst Chem Ind, Shanghai, Peoples R China
来源：
JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS | 2011年 / 54卷 / 04期
关键词：
isotopically labelled synthesis; N-15; melamine; cyanuric acid; labelled; synthesis; internal standards; CYANURIC ACID; MELAMINE; CATS;
D O I：
10.1002/jlcr.1835
中图分类号：
Q5 [生物化学];
学科分类号：
071010 ; 081704 ;
摘要：
This report presents an efficient syntheses of two labelled internal standards [N-15(3)] melamine and [C-13(3)] cyanuric acid with the common substrates [N-15]NH4Cl and [C-13] urea, respectively. Both standards with excellent isotopic and chemical purities were prepared in good yields and could be used as internal standards without further purification.
引用
收藏
页码：171 / 172
页数：2
相关论文
共 50 条
  • [1] Preparation of [13C3]-melamine and [13C3]-cyanuric acid and their application to the analysis of melamine and cyanuric acid in meat and pet food using liquid chromatography-tandem mass spectrometry
    Varelis, P.
    Jeskelis, R.
    FOOD ADDITIVES AND CONTAMINANTS PART A-CHEMISTRY ANALYSIS CONTROL EXPOSURE & RISK ASSESSMENT, 2008, 25 (10): : 1208 - 1215
  • [2] Synthesis of 13C3, 15N4-labeled factor Xa inhibitor
    Guilford, WJ
    Dallas, J
    Arnaiz, D
    JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS, 2001, 44 (04): : 247 - 256
  • [3] Synthesis of [13C3]-B6 Vitamers Labelled at Three Consecutive Positions Starting from [13C3]-Propionic Acid
    Bachmann, Thomas
    Rychlik, Michael
    MOLECULES, 2018, 23 (09):
  • [4] The synthesis of [3,4,1′-13C3]genistein
    Oldfield, Mark F.
    Chen, Lirong
    Botting, Nigel P.
    JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS, 2007, 50 (13-14): : 1266 - 1271
  • [5] The effects of isotope-labeled analogs on the LC-IDMS measurement by comparison of ESI responses and matrix effect of melamine, 13C3-melamine, 13C3+15N3-melamine, and 15N3-melamine
    Xiu Qin Li
    Qing He Zhang
    Zong Yang
    Hong Mei Li
    Dong Feng Huang
    Analytical and Bioanalytical Chemistry, 2017, 409 : 3233 - 3243
  • [6] The effects of isotope-labeled analogs on the LC-IDMS measurement by comparison of ESI responses and matrix effect of melamine, 13C3-melamine, 13C3+15N3-melamine, and 15N3-melamine
    Li, Xiu Qin
    Zhang, Qing He
    Yang, Zong
    Li, Hong Mei
    Huang, Dong Feng
    ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 2017, 409 (12) : 3233 - 3243
  • [7] Hyperpolarized [6-13C,15N3]-Arginine as a Probe for in Vivo Arginase Activity
    Cho, Andrew
    Eskandari, Roozbeh
    Granlund, Kristin L.
    Keshari, Kayvan R.
    ACS CHEMICAL BIOLOGY, 2019, 14 (04) : 665 - 673
  • [8] The syntheses of [14C] and [13C2,15N3]apirepitant
    Elmore, CS
    Dean, DC
    Zhang, Y
    Mellilo, DG
    JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS, 2004, 47 (12): : 837 - 846
  • [9] The 4051 Å Comet Band of 13C3
    Haddad, M. A.
    Zhao, D.
    Linnartz, H.
    Ubachs, W.
    DIFFUSE INTERSTELLAR BANDS, 2014, 9 (297): : 297 - 299
  • [10] Solvent Effects in Hyperpolarization of 15N Nuclei in [15N3]Metronidazole and [15N3]Nimorazole Antibiotics via SABRE-SHEATH
    Yi, Anna P.
    Salnikov, Oleg G.
    Burueva, Dudari B.
    Chukanov, Nikita V.
    Chekmenev, Eduard Y.
    Koptyug, Igor V.
    ANALYSIS & SENSING, 2024, 4 (06):
12345