Synthesis of Indenopyridine Derivatives via MgI2-Promoted [2+4] Cycloaddition Reaction of In-situ Generated 2-Styrylmalonate from Donor-Acceptor Cyclopropanes and Chalconimines

被引：31
|
作者：
Verma, Kamal [1 ]
Banerjee, Prabal [1 ]
机构：
[1] Indian Inst Technol Ropar, Dept Chem, Nangal Rd, Rupnagar 140001, Punjab, India
来源：
ADVANCED SYNTHESIS & CATALYSIS | 2018年 / 360卷 / 19期
关键词：
2-styrylmalonate; donor-acceptor cyclopropanes; indenopyridine; chalconimines; DIELS-ALDER REACTIONS; POTENTIAL ANTIDEPRESSANTS; MJ-III-65; NSC-706744; 4+2 ANNULATION; ROUTE; COMPLEXES; ANALOGS;
D O I：
10.1002/adsc.201800598
中图分类号：
O69 [应用化学];
学科分类号：
081704 ;
摘要：
An unexpected MgI2-promoted [2 + 4] cycloaddition reaction of in-situ generated 2-styrylmalonate from donor-acceptor cyclopropanes with chalconimines to synthesize highly substituted indenopyridine derivatives under the mild reaction conditions have been developed. Additionally, these derivatives were utilized for the synthesis of highly substituted 9-membered lactam by oxidative C=C bond cleavage and spiro [oxoindane-pyrrolidine] derivative via Meinwald type rearrangement.
引用
收藏
页码：3687 / 3692
页数：6
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