The effect of packaging materials on the stability of sunscreen emulsions

被引：11
|
作者：
Santoro, MIRM [1 ]
Oliveira, DAGDE [1 ]
Kedor-Hackmann, ERM [1 ]
Singh, AK [1 ]
机构：
[1] Univ Sao Paulo, Fac Pharmaceut Sci, Dept Pharm, BR-05315970 Sao Paulo, Brazil
来源：
INTERNATIONAL JOURNAL OF PHARMACEUTICS | 2005年 / 297卷 / 1-2期
基金：
巴西圣保罗研究基金会;
关键词：
cosmetic products; emulsions; sunscreens; packaging materials; HPLC; rheology;
D O I：
10.1016/j.ijpharm.2005.03.021
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
The purpose of this research was to study the stability of a emulsion containing UVA, UVB and infrared sunscreens after storage in different types of packaging materials (glass and plastic flasks; plastic and metallic tubes). The samples, emulsions containing benzophenone-3 (B-3), octyl methoxycinnamate (OM) and Phycocorail (R), were stored at 10, 25, 35 and 45 degrees C and representative samples were analyzed after 2, 7, 30, 60 and 90 days period. The stability studies were conducted by analyzing samples at pre-determined intervals by high performance liquid chromatography (HPLC) along with periodic rheological measurements. (c) 2005 Elsevier B.V. All rights reserved.
引用
收藏
页码：197 / 203
页数：7
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