In this paper, we define five parameters generalization of Fibonacci numbers that generalizes Fibonacci, Pell, Modified Pell, Jacobsthal, Narayana, Padovan, k-Fibonacci, k-Pell, Modified k-Pell, k-Jacobsthal numbers and Fibonacci p-numbers, distance Fibonacci numbers, (2, k)-distance Fibonacci numbers, generalized (k, r)-Fibonacci numbers in the distance sense by extending the definition of a distance in the recurrence relation with two parameters and adding three parameters in the definition of this distance, simultaneously. Tiling and combinatorial interpretations of generalized Fibonacci numbers are presented, and explicit formulas that allow us to calculate the nth number are given. Also generating functions and some identities for these numbers are obtained.