Diabetes mellitus and chronic kidney disease: Possibilities of prediction, early diagnosis, and nephroprotection in the 21st century

被引：5
|
作者：
Shestakova, M. V. [1 ,2 ]
机构：
[1] Minist Hlth Russia, Endocrinol Res Ctr, Moscow, Russia
[2] IM Sechenov First Moscow State Med Univ, Minist Hlth Russia, Moscow, Russia
来源：
TERAPEVTICHESKII ARKHIV | 2016年 / 88卷 / 06期
关键词：
diabetes mellitus; chronic kidney disease; diabetic nephropathy; urinary biomarkers; urine proteomics; genetic prediction; nephroprotection; NEPHROPATHY;
D O I：
10.17116/terarkh201688684-88
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
The review gives data on the prognostic value of genetic markers when analyzing the risk of chronic kidney disease in diabetes mellitus, those on new possibilities of early diagnosis of diabetic nephropathy using urinary biomarkers (nephrinuria, podocinuria) and proteomic urinalysis at the stage of normoalbuminuria. The interpretation of the index microalbuminuria in type 2 diabetes is critically analyzed. The nephroprotective properties of novel classes of glucose-lowering drugs, such as incretins and gliflozins, are considered.
引用
收藏
页码：84 / 88
页数：5
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