A Review of Electrostatic Measurement Techniques for Aerosol Drug Delivery to the Lung: Implications in Aerosol Particle Deposition

被引：14
|
作者：
Hoe, Susan [1 ]
Young, Paul M. [1 ]
Traini, Daniela [1 ]
机构：
[1] Univ Sydney, Adv Drug Delivery Grp, Fac Pharm, Sydney, NSW 2006, Australia
来源：
JOURNAL OF ADHESION SCIENCE AND TECHNOLOGY | 2011年 / 25卷 / 4-5期
关键词：
Pharmaceutical aerosols; electrostatic charge; Faraday pail; ELPI; E-SPART; PDA; eNGI; DRY POWDER INHALERS; CHARGE-DISTRIBUTION; BIPOLAR CHARGE; SIZE; TRIBOELECTRIFICATION; CARRIER; DISTRIBUTIONS; PERFORMANCE; HUMIDITY; SURFACE;
D O I：
10.1163/016942410X525632
中图分类号：
TQ [化学工业];
学科分类号：
0817 ;
摘要：
Electrostatic properties of formulation components play an important role in inhalation products. Suitable measurement of charge distribution will, therefore, lead to better control of inhalation formulation manufacture. Advances in this field have been made in the past few years but, real time, direct techniques still need to be developed further to obtain a precise, accurate and easy to use measurement of electrically charged aerosolised powders. This short review presents an overview of the various techniques present in literature for measurement of charge applicable to inhalation dosage forms. (C) Koninklijke Brill NV, Leiden, 2011
引用
收藏
页码：385 / 405
页数：21
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