Quantum Dot Superluminescent Diodes for Optical Coherence Tomography: Skin Imaging

被引：27

作者：

Krstajic, Nikola ^{[1
]}

Smith, Louise E. ^{[2
]}

Matcher, Stephen John ^{[2
]}

Childs, David T. D. ^{[3
]}

Bonesi, Marco ^{[2
]}

Greenwood, Purnima Daisy Lydia ^{[3
]}

Hugues, Maxime ^{[3
]}

Kennedy, Kenneth ^{[3
]}

Hopkinson, Mark ^{[3
]}

Groom, Kristian Michael ^{[3
]}

MacNeil, Sheila ^{[2
]}

Hogg, Richard A. ^{[3
]}

Smallwood, Rod ^{[1
]}

机构：

[1] Univ Sheffield, Dept Comp Sci, Sheffield S1 4DP, S Yorkshire, England

[2] Univ Sheffield, Dept Mat Engn, Sheffield S1 3JD, S Yorkshire, England

[3] Univ Sheffield, Dept Elect & Elect Engn, Sheffield S1 3JD, S Yorkshire, England

来源：

IEEE JOURNAL OF SELECTED TOPICS IN QUANTUM ELECTRONICS | 2010年 / 16卷 / 04期

基金：

英国生物技术与生命科学研究理事会;

关键词：

Optical coherence tomography (OCT); skin imaging; superluminescent diodes; tissue engineering; LIGHT-EMITTING-DIODES; EPIDERMAL THICKNESS; HIGH-POWER; KERATINOCYTES; TISSUE; SCATTERING; DELAY;

D O I：

10.1109/JSTQE.2009.2038597

中图分类号：

TM [电工技术]; TN [电子技术、通信技术];

学科分类号：

0808 ; 0809 ;

摘要：

We present a high-power (18 mW continuous wave exiting a single-mode fiber and 35 mW exiting the facet), broadband (85 nm full-width at half-maximum) quantum dot-based superluminescent diode, and apply it to a time-domain optical coherence tomography (OCT) setup. First, we test its performance with increasing optical feedback. Then we demonstrate its imaging properties on tissue-engineered (TE) skin and in vivo skin. OCT allows the tracking of epidermal development in TE skin, while the higher power source allows better sensitivity and depth penetration for imaging of in vivo skin layers.

引用

页码：748 / 754

页数：7

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