Circadian variation in restless legs syndrome

被引：30
|
作者：
Baier, P. C. [1 ]
Trenkwalder, C.
机构：
[1] Univ Gottingen, Dept Clin Neurophysiol, Gottingen, Germany
[2] Univ Kiel, Dept Psychiat & Psychotherapy, D-24098 Kiel, Germany
[3] Paracelsus Elena Klin, Kassel, Germany
来源：
SLEEP MEDICINE | 2007年 / 8卷 / 06期
关键词：
restless legs syndrome; RLS; circadian rhythm; dopamine; iron;
D O I：
10.1016/j.sleep.2006.10.011
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
Restless legs syndrome (RLS) is a clinical disorder that currently is not characterized by a uniform pathophysiologiocal definition. The diagnosis of RLS requires circadian variation in symptoms, although no path ophysiological basis has been verified. Clinical observations and research studies confirm the variation in symptoms, of both sensory and motor components, over the course of the day. This contribution reviews the current literature on circadian variation in RLS and discusses potential intrinsic and extrinsic causes. (c) 2006 Elsevier B.V. All rights reserved.
引用
收藏
页码：645 / 650
页数：6
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