A novel synthesis of 5-perfluorophenyl 4,5-dihydro-1H-pyrazoles in THF or water

被引：4
|
作者：
Pang, Wan
Zhu, Shifa
Jiang, Huanfeng
Zhu, Shizheng [1 ]
机构：
[1] S China Univ Technol, Coll Chem, Guangzhou 510640, Peoples R China
[2] Chinese Acad Sci, Shanghai Inst Organ Chem, Key Lab Organofluorine Chem, Shanghai 200032, Peoples R China
来源：
JOURNAL OF FLUORINE CHEMISTRY | 2007年 / 128卷 / 11期
基金：
中国国家自然科学基金;
关键词：
perfluorobenyl; pyrazoles; alpha; beta-unsaturated carbonyl compounds; water;
D O I：
10.1016/j.jfluchem.2007.06.010
中图分类号：
O61 [无机化学];
学科分类号：
070301 ; 081704 ;
摘要：
5-Perfluorophenyl 4,5-dihydro-1H-pyrazoles were synthesized from 1,3-dipolar cycloaddition reaction of perfluorobenyl 2,4,6-triisopropyl-benzenesulfonylhydrazone and alpha,beta-unsaturated carbonyl compounds or acrylonitrile in THF or water. It was worthy to note that better results were obtained when water was employed as the solvent, which was considered as an effective, economic and environmentally friendly method to synthesize these pyrazole derivatives. (c) 2007 Elsevier B.V. All rights reserved.
引用
收藏
页码：1379 / 1384
页数：6
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