Stability of piecewise-linear models of genetic regulatory networks

被引:2
|
作者
Lin Peng [1 ]
Qin Kai-Yu [1 ]
Wu Hai-Yan [1 ]
机构
[1] Univ Elect Sci & Technol China, Inst Aeronaut & Astronaut, Chengdu 610054, Peoples R China
基金
中国国家自然科学基金;
关键词
genetic regulatory networks; piecewise-linear model; Lyapunov function; SIMULATION;
D O I
10.1088/1674-1056/20/10/108701
中图分类号
O4 [物理学];
学科分类号
0702 ;
摘要
This paper investigates the stability of the equilibria of the piecewise-linear models of genetic regulatory networks on the intersection of the thresholds of all variables. It first studies circling trajectories and derives some stability conditions by quantitative analysis in the state transition graph. Then it proposes a common Lyapunov function for convergence analysis of the piecewise-linear models and gives a simple sign condition. All the obtained conditions are only related to the constant terms on the right-hand side of the differential equation after bringing the equilibrium to zero.
引用
收藏
页数:10
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