Chlorinated Iridoid Glucosides from Veronica longifolia and Their Antioxidant Activity

被引：30
|
作者：
Jensen, Soren R. [1 ]
Gotfredsen, Charlotte H. [1 ]
Harput, U. Sebnem [2 ]
Saracoglu, Iclal [2 ]
机构：
[1] Tech Univ Denmark, Dept Chem, DK-2800 Lyngby, Denmark
[2] Hacettepe Univ, Fac Pharm, Dept Pharmacognosy, TR-06100 Ankara, Turkey
来源：
JOURNAL OF NATURAL PRODUCTS | 2010年 / 73卷 / 09期
关键词：
OFFICINALIS L SCROPHULARIACEAE; SPECTROSCOPY; PLANTAGINACEAE; CONSTITUENTS; MARKERS; C-13;
D O I：
10.1021/np100366k
中图分类号：
Q94 [植物学];
学科分类号：
071001 ;
摘要：
From Veronica longifolia were isolated three chlorinated iridoid glucosides, namely, asystasioside E (6) and its 6-O-esters 6a and 6b, named longifoliosides A and B, respectively. The structures of 6a and 6b were proved by analysis of their spectroscopic data and by conversion to the catalpol ester verproside (5a) or to catalpol (5), respectively. The configuration of the previously known vanilloyl analogue, urphoside B, was shown to be the 6 beta-epimer (6c) of the structure originally reported. Longifoliosides A (6a) and B (6b) were found to exhibit radical-scavenging activity against nitric oxide, superoxide, and 2,2-diphenyl-1-picrylhydrazyl radicals.
引用
收藏
页码：1593 / 1596
页数：4
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