Therapies for non-alcoholic fatty liver disease: A 2022 update

被引:5
|
作者
Shen, Katie [1 ,3 ]
Singh, Achintya D. [1 ]
Esfeh, Jamak Modaresi [2 ]
Wakim-Fleming, Jamile [2 ]
机构
[1] Cleveland Clin Fdn, Dept Internal Med, Cleveland, OH 44195 USA
[2] Cleveland Clin Fdn, Dept Gastroenterol & Hepatol, Cleveland, OH 44195 USA
[3] Cleveland Clin Fdn, Dept Internal Med, 9500 Euclid Ave, Cleveland, OH 44195 USA
关键词
Non-alcoholic fatty liver disease; Non-alcoholic steatohepatitis; Treatment; OBETICHOLIC ACID; ADIPOSE-TISSUE; INFLAMMATION; PLACEBO; MULTICENTER; MANAGEMENT; FIBROSIS; RECEPTOR; DIET;
D O I
10.4254/wjh.v14.i9.1718
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
The incidence of non-alcoholic fatty liver disease (NAFLD) is rapidly increasing and lifestyle interventions to treat this disease by addressing the underlying metabolic syndrome are often limited. Many pharmacological interventions are being studied to slow or even reverse NAFLD progression. This review for hepatologists aims to provide an updated understanding of the pathogenesis of NAFLD, current recommended therapies, and the most promising treatment options that are currently under development.
引用
收藏
页码:1718 / 1729
页数:12
相关论文
共 50 条
  • [1] Therapies for non-alcoholic fatty liver disease: A 2022 update
    Katie Shen
    Achintya D Singh
    Jamak Modaresi Esfeh
    Jamile Wakim-Fleming
    [J]. World Journal of Hepatology, 2022, 14 (09) : 1718 - 1729
  • [2] An update on non-alcoholic fatty liver disease
    Méndez-Sánchez, N
    Chávez-Tapia, NC
    Uribe, M
    [J]. REVISTA DE INVESTIGACION CLINICA-CLINICAL AND TRANSLATIONAL INVESTIGATION, 2004, 56 (01): : 72 - 82
  • [3] An update on non-alcoholic fatty liver disease and non-alcoholic steatohepatitis in Asia
    Hsu, Ching-Sheng
    Kao, Jia-Horng
    [J]. EXPERT REVIEW OF GASTROENTEROLOGY & HEPATOLOGY, 2017, 11 (08) : 759 - 772
  • [4] Update on non-alcoholic fatty liver disease in children
    Papandreou, Dimitrios
    Rousso, Israel
    Mavromichalis, Loannis
    [J]. CLINICAL NUTRITION, 2007, 26 (04) : 409 - 415
  • [5] Non-alcoholic fatty liver disease and dyslipidemia: An update
    Katsiki, Niki
    Mikhailidis, Dimitri P.
    Mantzoros, Christos S.
    [J]. METABOLISM-CLINICAL AND EXPERIMENTAL, 2016, 65 (08): : 1109 - 1123
  • [6] Update on Non-alcoholic Fatty Liver Disease in Children
    Lee, Kyung-Hun
    [J]. PEDIATRIC GASTROENTEROLOGY HEPATOLOGY & NUTRITION, 2009, 12 : 62 - 71
  • [7] Current and Emerging Therapies for Non-alcoholic Fatty Liver Disease
    Patel, Samarth Siddharth
    Siddiqui, Mohammad Shadab
    [J]. DRUGS, 2019, 79 (01) : 75 - 84
  • [8] Current and Emerging Therapies for Non-alcoholic Fatty Liver Disease
    Samarth Siddharth Patel
    Mohammad Shadab Siddiqui
    [J]. Drugs, 2019, 79 : 75 - 84
  • [9] Non-alcoholic fatty liver disease and the metabolic syndrome: An update
    Rector, R. Scott
    Thyfault, John P.
    Wei, Yongzhong
    Ibdah, Jamal A.
    [J]. WORLD JOURNAL OF GASTROENTEROLOGY, 2008, 14 (02) : 185 - 192
  • [10] Non-alcoholic fatty liver disease and the metabolic syndrome:An update
    R Scott Rector
    John P Thyfault
    Jamal A Ibdah
    [J]. World Journal of Gastroenterology, 2008, (02) : 185 - 192