Green solvents for enhanced impregnation processes in biomedicine

被引：27
|
作者：
Barros, Alexandre A. [1 ,2 ]
Silva, Joana M. [1 ,2 ]
Craveiro, Rita [3 ]
Paiva, Alexandre [3 ]
Reis, Rui L. [1 ,2 ]
Duarte, Ana Rita C. [1 ,2 ]
机构：
[1] Univ Minho, Res Grp Biomat Biodegradable & Biomimet 3Bs, European Inst Excellence Tissue Engn & Regenerat, Avepk, P-4805017 Barco, Guimaraes, Portugal
[2] ICVS 3Bs PT Govt Associated Lab, Braga, Guimaraes, Portugal
[3] Univ Nova Lisboa, LAQV REQUIMTE, Dept Quim, Fac Ciencias & Tecnol, P-2829516 Caparica, Portugal
来源：
CURRENT OPINION IN GREEN AND SUSTAINABLE CHEMISTRY | 2017年 / 5卷
关键词：
DEEP EUTECTIC SOLVENTS; SUPERCRITICAL CARBON-DIOXIDE; DRUG-DELIVERY; CO2; SCAFFOLDS; SPECTROSCOPY; KETOPROFEN; IBUPROFEN; IMPLANTS; EXTRACT;
D O I：
10.1016/j.cogsc.2017.03.014
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Supercritical carbon dioxide has been used as a green solvent due to their well-known potential in biomaterials impregnation. The versatility of this technique enables the loading of implants with Active Pharmaceutical Ingredients which present several benefits when compared with traditional techniques to impregnate active compounds. In this review, we have summarized the recent progresses achieved in supercritical CO2 assisted impregnation of active compounds and therapeutic deep eutectic systems for biomedical applications.
引用
收藏
页码：82 / 87
页数：6
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