Nutrition and neurodevelopmental outcomes in preterm infants: asystematic review

被引:60
|
作者
Chan, Stephanie H. T. [1 ]
Johnson, Mark J. [2 ,3 ,4 ]
Leaf, Alison A. [2 ,3 ,4 ]
Vollmer, Brigitte [5 ,6 ]
机构
[1] Univ Southampton, Fac Med, Mailpoint 801,South Acad Block,Tremona Rd, Southampton SO16 6YD, Hants, England
[2] Univ Hosp Southampton NHS Fdn Trust, NIHR Biomed Res Ctr Southampton, Southampton, Hants, England
[3] Univ Southampton, Mailpoint 801,South Acad Block,Tremona Rd, Southampton SO16 6YD, Hants, England
[4] Univ Hosp Southampton NHS Fdn Trust, Southampton Childrens Hosp, Dept Neonatal Med, Southampton, Hants, England
[5] Univ Southampton, Fac Med, Cli Neurosci, Clin & Expt Sci, Mailpoint 801,South Acad Block,Tremona Rd, Southampton SO16 6YD, Hants, England
[6] Univ Hosp Southampton NHS Fdn Trust, Southampton Childrens Hosp, Neonatal & Paediat Neurol, Southampton, Hants, England
基金
美国国家卫生研究院;
关键词
Infant; Low birthweight; Neurodevelopment; Nutrition; Very preterm; RANDOMIZED CONTROLLED-TRIAL; PARENTERAL AMINO-ACIDS; BIRTH-WEIGHT INFANTS; EARLY DIET; DEVELOPMENTAL OUTCOMES; HUMAN-MILK; GROWTH; BABIES; AGE; PERFORMANCE;
D O I
10.1111/apa.13344
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
A systematic review with meta-analysis was carried out to investigate the effects of increased nutritional intake, via either macronutrient or multinutrient intervention, during the neonatal period on neurodevelopmental outcomes in infants born at <32weeks of gestation or weighing <1501 g at birth. Conclusion: Although the relationship remains unclear, increased early nutrition may reduce neurodevelopmental impairment in this group of infants. Future research should focus on using standardised nutritional interventions and an agreed neurodevelopmental assessment battery.
引用
收藏
页码:587 / 599
页数:13
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