IL-2, IL-6 and IL-8 levels remain unaltered in the course of immunosuppressive therapy after renal transplantation

被引：3

作者：

Rysz, Jacek ^{[1
]}

Kocur, Eugeniusz ^{[1
]}

Blaszczak, Robert ^{[1
]}

Bartnicki, Piotr ^{[1
]}

Stolarek, Robert A. ^{[1
,2
]}

Piechota, Mariusz ^{[3
,4
]}

机构：

[1] Med Univ Lodz, Dept Family Med 2, PL-90549 Lodz, Poland

[2] Med Univ Lodz, Dept Expt & Clin Physiol, PL-92215 Lodz, Poland

[3] Med Univ Lodz, Univ Hosp Lodz 5, Dept Anaesthesiol, PL-90647 Lodz, Poland

[4] Med Univ Lodz, Univ Hosp Lodz 5, Intens Care Unit, PL-90647 Lodz, Poland

来源：

CENTRAL EUROPEAN JOURNAL OF MEDICINE | 2008年 / 3卷 / 02期

关键词：

cytokines; lymphocytes; transplantation; immune system;

D O I：

10.2478/s11536-008-0011-4

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Cytokines regulate the immune reactions elicited by renal transplantation (RT). This study was designed to investigate the blood serum levels of IL-2, IL-6, IL-8 in 25 RT patients (10 female and 15 male, mean 5.4 +/- 2.7 yrs after RT) three times over a six-month period during standard immunosuppressive therapy with cyclosporine A, azathioprine and prednisolone. The levels of IL-2, IL-6 and IL-8 were tested with ELISA Quantikine Human Interleukin Immunoassay (R&D Systems, detection level 7,0.7 and 10 mu g/cm(3), respectively). There was no significant alternation of blood serum levels of IL-2, IL-6 and IL-8 in the study patients.

引用

页码：199 / 202

页数：4

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