Evaluating the therapeutic efficacy of nano-drugs targeting epidermal growth factor receptor

被引：7
|
作者：
Zhao, Jing [1 ]
Li, Siying [1 ]
Pang, Xuelei [1 ]
Shan, Yuping [1 ]
机构：
[1] Changchun Univ Technol, Sch Chem & Life Sci, Adv Inst Mat Sci, Changchun 130012, Peoples R China
来源：
CHEMICAL COMMUNICATIONS | 2022年 / 58卷 / 16期
基金：
中国国家自然科学基金;
关键词：
EGF RECEPTOR; DELIVERY; ENDOCYTOSIS; CETUXIMAB; LIGAND;
D O I：
10.1039/d1cc06754k
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Epidermal growth factor receptor (EGFR) targeted nano-drugs facilitate effective diagnosis and treatment of cancer. Herein, the therapeutic efficacy of nano-drugs targeting EGFR was evaluated from the perspective of cell entry efficiency and induced cell mechanical properties using force tracing and nano-indentation techniques at the single particle/cell level in real time.
引用
收藏
页码：2726 / 2729
页数：4
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