Synthesis of greener silver nanoparticle-based chitosan nanocomposites and their potential antimicrobial activity against oral pathogens

被引:0
|
作者
Rajeshkumar, Shanmugam [1 ]
Tharani, Munusamy [1 ]
Rajeswari, Vijayarangan Devi [4 ]
Alharbi, Naiyf S. [5 ]
Kadaikunnan, Shine [5 ]
Khaled, Jamal M. [5 ]
Gopinath, Kasi [6 ]
Vijayakumar, Natesan [7 ]
Govindarajan, Marimuthu [2 ,3 ]
机构
[1] SIMATS, Dept Pharmacol, Saveetha Dent Coll & Hosp, Chennai 600077, Tamil Nadu, India
[2] Annamalai Univ, Dept Zool, Unit Vector Control Phytochem & Nanotechnol, Annamalainagar 608002, Tamil Nadu, India
[3] Govt Coll Women Autonomous, Dept Zool, Kumbakonam 612001, Tamil Nadu, India
[4] Vellore Inst Technol VIT, Sch BioSci & Technol, Dept Biomed Sci, Vellore 632014, Tamil Nadu, India
[5] King Saud Univ, Coll Sci, Dept Bot & Microbiol, Riyadh 11451, Saudi Arabia
[6] Yonsei Univ, Dept Packaging, 1 Yonseidae Gil, Wonju 26493, Gangwon Do, South Korea
[7] Annamalai Univ, Fac Sci, Dept Biochem & Biotechnol, Annamalainagar 608002, Tamil Nadu, India
关键词
green synthesis; silver nanoparticles; chitosan nanocomposite; Cissus arnottiana; LEAF EXTRACTS; SHAPE; AG;
D O I
10.1515/gps-2021-0060
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
In the present investigation, silver nanoparti-cles (AgNPs) and silver nanoparticle-based chitosan nano-composite were synthesized using Cissus arnottiana leaf extract. The biosynthesized nanoparticles and nanocom-posites were characterized using SEM, TEM, and AFM to uncover the morphological characteristics such as size and shape. The SEM image depicts the size of the nanocompo-site to be 30-40 nm and shape as spherical. The TEM results reveal the shape of the nanocomposite to be sphe-rical and size around 10-60 nm. The XRD results show the crystalline nature of the AgNPs-based chitosan nanocom-posite. The SAED analysis pattern seems to be concordant with the XRD results. The AFM image ensured the precise surface morphology of the synthesized silver nanocomposite in the 3-dimensional pattern. The antimicrobial efficacy of the biosynthesized AgNPs, AgNP nanocomposite, and chit-osan nanoparticles was tested against oral pathogens. The results revealed a potential antimicrobial effect, which states that it must be converted into nanomedicine to meet future biomedical needs.
引用
收藏
页码:658 / 665
页数:8
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