Cyclic nucleotide-gated channels -: mediators of NO:cGMP-regulated processes

被引：28

作者：

Biel, M ^{[1
]}

Sautter, A ^{[1
]}

Ludwig, A ^{[1
]}

Hofmann, F ^{[1
]}

Zong, XG ^{[1
]}

机构：

[1] Tech Univ Munich, Inst Pharmakol & Toxikol, D-80802 Munich, Germany

来源：

NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY | 1998年 / 358卷 / 01期

关键词：

cyclic nucleotide-gated channels; nitric oxide; cyclic GMP; cyclic AMP; calcium; gene family;

D O I：

10.1007/PL00005235

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

Cyclic nucleotide-gated (CNG) channels represent one of the three known cellular receptor classes for cGMP. Activation of CNG channels by binding of cyclic nucleotides to a site in the C-terminus results in opening of the channel pore, entry of Ca2+ into the cell and subsequent induction of Ca2+-dependent processes. In this review we will summarize new data on the complex molecular structure and the activation mechanism of CNG channels. In addition, we will discuss the role of CNG channels as mediators of NO:cGMP-dependent cellular processes.

引用

页码：140 / 144

页数：5

共 50 条

[1] Cyclic nucleotide-gated channels – mediators of NO:cGMP-regulated processes
M. Biel
Andrea Sautter
Andreas Ludwig
Franz Hofmann
Xiangang Zong
[J]. Naunyn-Schmiedeberg's Archives of Pharmacology, 1998, 358 : 140 - 144
[2] cGMP and cyclic nucleotide-gated channels participate in mouse sperm capacitation
Cisneros-Mejorado, Abraham
Sanchez Herrera, Daniel P.
[J]. FEBS LETTERS, 2012, 586 (02) : 149 - 153
[3] Cyclic nucleotide-gated channels in plants
Kaplan, Boaz
Sherman, Tal
Fromm, Hillel
[J]. FEBS LETTERS, 2007, 581 (12) : 2237 - 2246
[4] Regulation of cyclic nucleotide-gated channels
Bradley, J
Reisert, J
Frings, S
[J]. CURRENT OPINION IN NEUROBIOLOGY, 2005, 15 (03) : 343 - 349
[5] Cyclic nucleotide-gated ion channels
Kaupp, UB
Seifert, R
[J]. PHYSIOLOGICAL REVIEWS, 2002, 82 (03) : 769 - 824
[6] Cyclic nucleotide-gated ion channels
Menini, A.
Boccaccio, A.
Pifferi, S.
[J]. FEBS JOURNAL, 2006, 273 : 9 - 9
[7] Cyclic nucleotide-gated ion channels
Matulef, K
Zagotta, WN
[J]. ANNUAL REVIEW OF CELL AND DEVELOPMENTAL BIOLOGY, 2003, 19 : 23 - 44
[8] FAMILY OF CYCLIC NUCLEOTIDE-GATED IONIC CHANNELS
KAUPP, UB
ALTENHOFEN, W
BONIGK, W
EISMANN, E
LUDWIG, J
[J]. EUROPEAN JOURNAL OF NEUROSCIENCE, 1992, : 82 - 82
[9] Molecular mechanisms of cyclic nucleotide-gated channels
Zagotta, WN
[J]. JOURNAL OF BIOENERGETICS AND BIOMEMBRANES, 1996, 28 (03) : 269 - 278
[10] Molecular characterization of cyclic nucleotide-gated channels
Biel, M
Zong, XG
Sautter, A
Hofmann, F
[J]. NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY, 1998, 357 (04) : R1 - R1

← 1 2 3 4 5 →