Non-spherical nanostructures in nanomedicine: From noble metal nanorods to transition metal dichalcogenide nanosheets

被引：19

作者：

Makvandi, Pooyan ^{[1
]}

Zarepour, Atefeh ^{[2
]}

Zheng, Xuanqi ^{[3
]}

Agarwal, Tarun ^{[4
]}

Ghomi, Matineh ^{[5
,6
]}

Sartorius, Rossella ^{[7
]}

Zare, Ehsan Nazarzadeh ^{[5
]}

Zarrabi, Ali ^{[2
]}

Wu, Aimin ^{[3
]}

Maiti, Tapas Kumar ^{[4
]}

Smith, Bryan Ronain ^{[8
,9
,10
]}

Varma, Rajender S. ^{[11
]}

Tay, Franklin R. ^{[12
]}

Mattoli, Virgilio ^{[1
]}

机构：

[1] Ist Italiano Tecnol, Ctr Mat Inrefeaces, Viale Rinaldo Piaggio 34, I-56025 Pisa, Italy

[2] Sabanci Univ, Nanotechnol Res & Applicat Ctr SUNUM, TR-34956 Tuzla, Turkey

[3] Wenzhou Med Univ, Dept Orthopaed, Zhejiang Prov Key Lab Orthopaed, Affiliated Hosp & Yuying Childrens Hosp 2, Wenzhou, Peoples R China

[4] Indian Inst Technol Kharagpur, Dept Biotechnol, Kharagpur 721302, W Bengal, India

[5] Damghan Univ, Sch Chem, Damghan 3671641167, Iran

[6] Shahid Chamran Univ Ahvaz, Fac Sci, Chem Dept, Ahvaz 6153753843, Iran

[7] Natl Res Council CNR, Inst Biochem & Cell Biol IBBC, I-80131 Naples, Italy

[8] Michigan State Univ, Inst Quantitat Hlth Sci & Engn, Dept Biomed Engn, E Lansing, MI 48824 USA

[9] Stanford Univ, Dept Radiol, Stanford, CA 94305 USA

[10] Stanford Univ, Mol Imaging Program, Stanford, CA 94305 USA

[11] Palacky Univ Olomouc, Reg Ctr Adv Technol & Mat, Slechtitelu 27, Olomouc 78371, Czech Republic

[12] Augusta Univ, Coll Grad Studies, Augusta, GA 30912 USA

来源：

APPLIED MATERIALS TODAY | 2021年 / 24卷

关键词：

Anti-cancer therapy; Cancer diagnosis; Endocytosis mechanism; MXene; Transition metal dichalcogenides; Tissue engineering; RECEPTOR-MEDIATED ENDOCYTOSIS; MESOPOROUS SILICA NANOPARTICLES; CELL-PENETRATING PEPTIDES; IRON-OXIDE NANOPARTICLES; GOLD NANORODS; DRUG-DELIVERY; IN-VIVO; SURFACE-CHEMISTRY; STEM-CELLS; NANOCOMPOSITE SCAFFOLDS;

D O I：

10.1016/j.apmt.2021.101107

中图分类号：

T [工业技术];

学科分类号：

08 ;

摘要：

Non-spherical metal nanomaterials such as noble metal or transition metal dichalcogenides and MXenes have been employed in different biomedical facets. Because the biological properties of these nanocompounds are governed by their architecture and composition, such factors should be considered prior to their adoption for clinical use. The architecture of metal-based nanomaterials affects cell viability by virtue of the variable geometry of these nanomaterials as well as their physicochemical interactions with mammalian cell membranes. In the present review, the effects of parameters such as interfacial interaction and aspect ratio on cellular uptake of non-spherical metallic nanomaterials will be discussed. The application of these nanomaterials as biosensors, in cancer diagnosis and therapy, tissue engineering and regenerative medicine will also be thoroughly reviewed. (c) 2021 Elsevier Ltd. All rights reserved.

引用

页数：30

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