A Phenylacetylated Peptide, JBIR-96, Isolated from Streptomyces sp RI051-SDHV6

被引：8
|
作者：
Ueda, Jun-ya [1 ]
Izumikawa, Miho [1 ]
Kozone, Ikuko [1 ]
Yamamura, Hideki [2 ]
Hayakawa, Masayuki [2 ]
Takagi, Motoki [1 ]
Shin-ya, Kazuo [3 ]
机构：
[1] Japan Biol Informat Consortium JBIC, Biomed Informat Res Ctr BIRC, Koto Ku, Tokyo 1350064, Japan
[2] Univ Yamanashi, Interdisciplinary Grad Sch Med & Engn, Kofu, Yamanashi 4008511, Japan
[3] Natl Inst Adv Ind Sci & Technol, Biomed Informat Res Ctr BIRC, Koto Ku, Tokyo 1350064, Japan
来源：
JOURNAL OF NATURAL PRODUCTS | 2011年 / 74卷 / 05期
基金：
日本学术振兴会;
关键词：
METABOLIC PRODUCTS; MICROORGANISMS; INHIBITOR;
D O I：
10.1021/np200054s
中图分类号：
Q94 [植物学];
学科分类号：
071001 ;
摘要：
Searching for metabolites from Streptomyces sp. RI051-SDHV6 resulted in the discovery of a novel peptide, JBIR-96 (1). The structure of 1 was established as an N-phenylacetylated pentapeptide involving a cysteic acid and a peptide lactone structure by extensive NMR and MS analyses. In addition, the absolute configuration of 1 was established by Marfey's and modified Mosher's methods.
引用
收藏
页码：1344 / 1347
页数：4
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