Thrombotic thrombocytopenic purpura (TTP) is a rarely seen complicating systemic lupus erythematosus (SLE). The diagnosis of TTP in a setting of SLE is challenging since both share common features including thrombotic microangiopathy. We report two cases of SLE with TTP - one with a good response when cyclophosphamide was given early with plasmapheresis and steroids: the other with a poor outcome in a patient given cyclophosphamide late in the course of the disease.
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Univ Milan, Osped G Pini, Dept Clin Sci & Community Hlth, Div Rheumatol, Milan, ItalyUniv Milan, Osped G Pini, Dept Clin Sci & Community Hlth, Div Rheumatol, Milan, Italy
Gerosa, M.
Gualtierotti, R.
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Univ Milan, Osped G Pini, Dept Clin Sci & Community Hlth, Div Rheumatol, Milan, ItalyUniv Milan, Osped G Pini, Dept Clin Sci & Community Hlth, Div Rheumatol, Milan, Italy
Gualtierotti, R.
Pisati, M.
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Univ Milan, Osped G Pini, Dept Clin Sci & Community Hlth, Div Rheumatol, Milan, ItalyUniv Milan, Osped G Pini, Dept Clin Sci & Community Hlth, Div Rheumatol, Milan, Italy
Pisati, M.
Meroni, P. L.
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Univ Milan, Osped G Pini, Dept Clin Sci & Community Hlth, Div Rheumatol, Milan, ItalyUniv Milan, Osped G Pini, Dept Clin Sci & Community Hlth, Div Rheumatol, Milan, Italy