Synthesis of C2-symmetric sulfide and its first application in highly enantioselective synthesis of chiral aziridines

被引：10

作者：

Gui, Yuan ^{[1
]}

Shen, Sheng ^{[1
]}

Wang, Hai-Yang ^{[1
]}

Li, Zhi-Yi ^{[1
]}

Huang, Zhi-Zhen ^{[1
]}

机构：

[1] Nanjing Univ, Sch Chem & Chem Engn, Nanjing 210093, Peoples R China

来源：

CHEMISTRY LETTERS | 2007年 / 36卷 / 12期

关键词：

D O I：

10.1246/cl.2007.1436

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A C-2-symmetric sulfide 6 has been synthesized from cheap L-tartaric acid. It was found that sulfide 6 could perform a tandem reaction with benzyl bromide and tosyl imines to give (2S.3S)-aziridines 9a-9g with good to excellent enantioseletivities (up to 96% ee).

引用

页码：1436 / 1437

页数：2

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