The frequency of HLA class I alleles in Japanese patients with bone marrow failure

被引：0
|
作者：
Shichishima, Tsutomu [1 ,2 ,3 ]
Noji, Hideyoshi [1 ]
Ikeda, Kazuhiko [1 ]
Akutsu, Kazuko [1 ]
Maruyama, Yukio [1 ]
机构：
[1] Fukushima Med Univ, Dept Internal Med 1, 1 Hikariga Oka, Fukushima, Fukushima 9601295, Japan
[2] Fukushima Res Inst Environm & Med, Fukushima, Japan
[3] Fukushima Prefectural Ohno Hosp, Internal Med, Fukushima, Japan
来源：
HAEMATOLOGICA | 2006年 / 91卷 / 06期
关键词：
D O I：
暂无
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
The frequencies of the HLA-B*4002 and HLA-A*0206 alleles in patients with aplastic anemia (AA) (n=32; 21.9%) and paroxysmal nocturanl hemoglobinuria (PNH) (n=24; 22.9%), respectively, were significantly different from those in controls (n=371; 8.6%, p<0.002 and 7.7%, p<0.001, respectively), suggesting that each specific allele in AA or PNH may be related to the immunologic pathophysiology of these disorders.
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页码：856 / 857
页数：2
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