Acute lymphoblastic leukemia in children with associated genetic conditions other than Down's syndrome. The AIEOP experience

被引：0

作者：

Ziino, Ottavio ^{[1
]}

Rondelli, Roberto ^{[2
]}

Micalizzi, Concetta ^{[3
]}

Luciani, Matteo ^{[4
]}

Conter, Valentino ^{[5
]}

Arico, Maurizio ^{[1
]}

机构：

[1] Osped Bambini G Di Cristina, Oncoematol Pediat, Palermo, Italy

[2] Univ Bologna, Oncoematol Pediat & Terapia Cellulare, Bologna, Italy

[3] Ist Giannina Gaslini, Oncoematol Pediat, Genoa, Italy

[4] IRCCS Osped Pediat Bambino Gesu, Oncoematol Pediat, Rome, Italy

[5] Univ Milano Bicocca, Osped San Gerardo, Clin Pediat, Monza, Italy

来源：

HAEMATOLOGICA | 2006年 / 91卷 / 01期

关键词：

D O I：

暂无

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

We retrospectively reviewed the databases of seven studies on acute lymphoblastic leukemia (ALL) by the Associazione Italiana Ematologia Oncologia Pediatrica (AIEOP) to identify patients with associated genetic disease, other than Down's syndrome. Forty-two patients were reported to have associated genetic conditions that included beta-thalassemia (n=10), ataxia-telangiectasia (n=5), neurofibromatosis (n=3), Sotos syndrome (n=2) and other individual conditions. Patients with ataxia-telangiectasia, all with T-cell ALL, had a higher frequency of adverse events.

引用

页码：139 / 140

页数：2

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