Rhodamine-based fluorogenic probe for imaging biological thiol

被引：97
|
作者：
Shibata, Aya [1 ]
Furukawa, Kazuhiro [1 ,2 ]
Abe, Hiroshi [1 ]
Tsuneda, Satoshi [2 ]
Ito, Yoshihiro [1 ]
机构：
[1] RIKEN, Discovery Res Inst, Nano Med Engn Lab, Wako, Saitama 3510198, Japan
[2] Waseda Univ, Dept Life Sci & Med Biosci, Shinjuku Ku, Tokyo 1698555, Japan
来源：
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 2008年 / 18卷 / 07期
关键词：
thiol; imaging; fluorescence; probe; synthesis;
D O I：
10.1016/j.bmcl.2008.03.014
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
We have developed a new fluorescent probe for biological thiol. The probe was synthesized by the modi. cation of the 2,4-dinitrobenzenesulfonyl group with rhodamine 110. The selective detection of thiol species such as cysteine or glutathione was achieved in biological conditions. Moreover, the probe was successfully applied to the imaging of thiol species in living human cells. (C) 2008 Elsevier Ltd. All rights reserved.
引用
收藏
页码：2246 / 2249
页数：4
相关论文
共 50 条
  • [1] Asymmetric Rhodamine-Based Fluorescent Probe for Multicolour In Vivo Imaging
    Iwatate, Ryu J.
    Kamiya, Mako
    Urano, Yasuteru
    CHEMISTRY-A EUROPEAN JOURNAL, 2016, 22 (05) : 1696 - 1703
  • [2] Rhodamine-based fluorescent probe for dynamic STED imaging of mitochondria
    Gao, Xinwei
    Cai, Songtao
    Wang, Luwei
    Guo, Yong
    Liu, Liwei
    Weng, Xiaoyu
    Huang, Kun
    Yan, Wei
    Qu, Junle
    BIOMEDICAL OPTICS EXPRESS, 2024, 15 (03) : 1595 - 1604
  • [3] RHODAMINE-BASED COMPOUNDS AS FLUOROGENIC SUBSTRATES FOR SERINE PROTEINASES
    LEYTUS, SP
    MELHADO, LL
    MANGEL, WF
    BIOCHEMICAL JOURNAL, 1983, 209 (02) : 299 - 307
  • [4] Covalent labeling of mitochondria with a photostable fluorescent thiol-reactive rhodamine-based probe
    Wu, Shuqi
    Song, Yunlong
    Li, Zhu
    Wu, Zhisheng
    Han, Jiahuai
    Han, Shoufa
    ANALYTICAL METHODS, 2012, 4 (06) : 1699 - 1703
  • [5] Rhodamine-Based Cyclic Hydroxamate as Fluorescent pH Probe for Imaging of Lysosomes
    Kim, Young Ju
    Jang, Mina
    Roh, Jongtae
    Lee, Yoon Jeong
    Moon, Hee Jung
    Byun, Jimin
    Wi, Jihyun
    Ko, Sung-Kyun
    Tae, Jinsung
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2023, 24 (20)
  • [6] A rhodamine-based highly specific fluorescent probe for the in situ and in vivo imaging of the biological signalling molecule salicylic acid
    Wang, Pei-Yi
    Luo, Xue
    Yang, Lin-Lin
    Zhao, Yuan-Chao
    Dong, Rong
    Li, Zhong
    Yang, Song
    CHEMICAL COMMUNICATIONS, 2019, 55 (53) : 7691 - 7694
  • [7] Fluorogenic Rhodamine-Based Chemigenetic Biosensor for Monitoring Cellular NADPH Dynamics
    Chang, Huimin
    Clemens, Simon
    Gao, Pingting
    Li, Quanlin
    Zhao, Hanqing
    Wang, Lehua
    Zhang, Jingye
    Zhou, Pinghong
    Johnsson, Kai
    Wang, Lu
    JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2024, 146 (30) : 20569 - 20576
  • [8] A rhodamine-based fluorescent probe for Hg2+ and its application for biological visualization
    Hu, Jiwen
    Hu, Zhangjun
    Cui, Yang
    Zhang, Xuanjun
    Gao, Hong-Wen
    Uvdal, Kajsa
    SENSORS AND ACTUATORS B-CHEMICAL, 2014, 203 : 452 - 458
  • [9] A novel rhodamine-based fluorescent probe for the fluorogenic and chromogenic detection of Pd2+ ions and its application in live-cell imaging
    Chen, Yu
    Chen, Bo
    Han, Yifeng
    SENSORS AND ACTUATORS B-CHEMICAL, 2016, 237 : 1 - 7
  • [10] A rhodamine-based chemosensor that works in the biological system
    Suresh, Moorthy
    Shrivastav, Anupama
    Mishra, Sandhya
    Suresh, E.
    Das, Amitava
    ORGANIC LETTERS, 2008, 10 (14) : 3013 - 3016
12345