SYSTEMIC SCLEROSIS PATIENTS EXHIBIT AN INCREASED FREQUENCY OF T CELLS AND NK CELLS WITH EFFECTOR/CYTOTOXIC PHENOTYPE.

被引:0
|
作者
Carvalheiro, Tiago [1 ]
Andrade, Angela [2 ]
Lemos, Magda [2 ]
Santiago, Mariana Galante [3 ]
Silva, Claudia [4 ]
Salvador, Maria Joao [3 ]
Pereira da Silva, Jose Antonio [3 ]
Paiva, Artur [1 ,2 ]
机构
[1] Portuguese Inst Blood & Transplantat, Blood & Transplantat Ctr Coimbra, Coimbra, Portugal
[2] Coll Hlth Technol Coimbra, Coimbra, Portugal
[3] Univ Hosp Ctr Coimbra, Rheumatol Dept, Coimbra, Portugal
[4] Univ Aveiro, P-3800 Aveiro, Portugal
关键词
D O I
10.1136/annrheumdis-2013-205124.118
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
A3.25
引用
收藏
页码:A52 / A52
页数:1
相关论文
共 50 条
  • [1] Increased cytotoxic T cells with effector phenotype in aplastic anemia and myelodysplasia
    Kook, H
    Zeng, WH
    Chen, GB
    Kirby, M
    Young, NS
    Maciejewski, JP
    EXPERIMENTAL HEMATOLOGY, 2001, 29 (11) : 1270 - 1277
  • [3] A Menage a Trois of Cytotoxic Effector Cells: γδ T Cells Suppress NK Cells but Not CTLs
    Kabelitz, Dieter
    CANCER IMMUNOLOGY RESEARCH, 2022, 10 (05) : 543 - 543
  • [4] Skin-Resident Effector Memory CD8+ CD28- T Cells Exhibit a Profibrotic Phenotype in Patients with Systemic Sclerosis
    Li, Gang
    Larregina, Adriana T.
    Domsic, Robyn T.
    Stolz, Donna B.
    Medsger, Thomas A., Jr.
    Lafyatis, Robert
    Fuschiotti, Patrizia
    JOURNAL OF INVESTIGATIVE DERMATOLOGY, 2017, 137 (05) : 1042 - 1050
  • [5] CD8 T cells expressing NK associated receptors are increased in melanoma patients and display an effector phenotype
    Javier G. Casado
    Rocío Soto
    Olga DelaRosa
    Esther Peralbo
    Maria del Carmen Muñoz-Villanueva
    Luis Rioja
    José Peña
    Rafael Solana
    Raquel Tarazona
    Cancer Immunology, Immunotherapy, 2005, 54 : 1162 - 1171
  • [6] CD8 T cells expressing NK associated receptors are increased in melanoma patients and display an effector phenotype
    Casado, JG
    Soto, R
    DelaRosa, O
    Peralbo, E
    Muñoz-Villanueva, MD
    Rioja, L
    Peña, J
    Solana, R
    Tarazona, R
    CANCER IMMUNOLOGY IMMUNOTHERAPY, 2005, 54 (12) : 1162 - 1171
  • [7] Increased frequency of T regulatory cells in systemic sclerosis displaying a markedly altered phenotype and compromised regulatory capacity
    Radstake, Timothy R.
    van Bon, Lenny
    Broen, Jasper
    Deng, Yanhui
    Cruikshank, William
    Lafyatis, Robbert
    ARTHRITIS AND RHEUMATISM, 2008, 58 (09): : S594 - S595
  • [8] Skin-resident effector memory CD8+CD28-T cells exhibit a pro-fibrotic phenotype in patients with systemic sclerosis
    Fuschiotti, Patrizia
    Larregina, Adriana T.
    Domsic, Robyn T.
    Stolz, Donna B.
    Medsger, Thomas A.
    Lafyatis, Robert A.
    JOURNAL OF IMMUNOLOGY, 2017, 198 (01):
  • [9] A NEW SUBSET OF NK CELLS, WITH ENHANCED CYTOTOXIC FUNCTION, IS INCREASED IN SYSTEMIC LUPUS ERYTHEMATOSUS PATIENTS
    Cruz Gonzalez, D. D. J.
    Baranda-Candido, L.
    Abud-Mendoza, C.
    Alcocer-Varela, J.
    Gonzalez-Amaro, R.
    Gomez-Martin, D.
    Monsivais-Urenda, A. E.
    ANNALS OF THE RHEUMATIC DISEASES, 2017, 76 : 774 - 774
  • [10] Lung microvascular endothelial cells exhibit a unique proliferative phenotype.
    Weathington, T
    Bhat, P
    Voelkel, N
    Stevens, T
    FASEB JOURNAL, 2002, 16 (04): : A406 - A406