A Bayesian approach for analyzing partly interval-censored data under the proportional hazards model

被引:19
|
作者
Pan, Chun [1 ]
Cai, Bo [2 ]
Wang, Lianming [3 ]
机构
[1] CUNY Hunter Coll, Dept Math & Stat, 695 Pk Ave, New York, NY 10065 USA
[2] Univ South Carolina, Dept Epidemiol & Biostat, Columbia, SC 29208 USA
[3] Univ South Carolina, Dept Stat, Columbia, SC 29208 USA
基金
美国国家卫生研究院;
关键词
Bayesian semiparametric; partly interval-censored; proportional hazards model; progression-free survival; FAILURE TIME MODEL; NONPARAMETRIC-ESTIMATION; 2ND-LINE TREATMENT; PANITUMUMAB; FOLFIRI; TESTS;
D O I
10.1177/0962280220921552
中图分类号
R19 [保健组织与事业(卫生事业管理)];
学科分类号
摘要
Partly interval-censored time-to-event data often occur in biomedical studies of diseases where periodic medical examinations for symptoms of interest are necessary. Recent decades have seen blooming methods and R packages for interval-censored data; however, the research effort for partly interval-censored data is limited. We propose an efficient and easy-to-implement Bayesian semiparametric method for analyzing partly interval-censored data under the proportional hazards model. Two simulation studies are conducted to compare the performance of the proposed method with two main Bayesian methods currently available in the literature and the classic Cox proportional hazards model. The proposed method is applied to a partly interval-censored progression-free survival data from a metastatic colorectal cancer trial.
引用
收藏
页码:3192 / 3204
页数:13
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