Enhancement of radio sensitivity of human medulloblastoma cells by histone deacetylase inhibitor valproic acid is associated with the activation of p21 and down-regulation of c-myc and survivin genes

被引：0
|
作者：
Li, X
Shu, Q
Munshi, A
Xia, Y
Chang, E
Woo, S
Lau, C
机构：
[1] Baylor Coll Med, Texas Childrens Canc Ctr, Houston, TX 77030 USA
[2] Univ Texas, MD Anderson Canc Ctr, Div Radiat Oncol, Houston, TX 77030 USA
[3] Sun Yat Sen Univ, Ctr Canc, Guangzhou, Peoples R China
来源：
NEURO-ONCOLOGY | 2005年 / 7卷 / 03期
关键词：
D O I：
暂无
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
424
引用
收藏
页码：389 / 390
页数：2
相关论文
共 27 条
  • [1] Effects of FK228, a novel histone deacetylase inhibitor, on tumor growth and expression of p21 and c-myc genes in vivo
    Sasakawa, Y
    Naoe, Y
    Inoue, T
    Sasakawa, T
    Matsuo, M
    Manda, T
    Mutoh, S
    CANCER LETTERS, 2003, 195 (02) : 161 - 168
  • [2] Histone Deacetylase Inhibitors Sensitize Human Non-small Cell Lung Cancer Cells to Ionizing Radiation Through Acetyl p53-Mediated c-myc Down-Regulation
    Seo, Sung-Keum
    Jin, Hyeon-Ok
    Woo, Sang-Hyeok
    Kim, Young-Sun
    An, Sungkwan
    Lee, Jae-Ho
    Hong, Seok-Il
    Lee, Kee-Ho
    Choe, Tae-Boo
    Park, In-Chul
    JOURNAL OF THORACIC ONCOLOGY, 2011, 6 (08) : 1313 - 1319
  • [3] Histone deacetylase inhibitors trichostatin A and valproic acid induce cell cycle arrest and p21 expression in immortalized human endometrial stromal cells
    Wu, Yan
    Guo, Sun-Wei
    EUROPEAN JOURNAL OF OBSTETRICS & GYNECOLOGY AND REPRODUCTIVE BIOLOGY, 2008, 137 (02) : 198 - 203
  • [4] DOWN-REGULATION OF C-MYC AND MAX GENES IS ASSOCIATED TO INHIBITION OF PROTEIN PHOSPHATASE 2A IN K562 HUMAN LEUKEMIA-CELLS
    LERGA, A
    BELANDIA, B
    DELGADO, MD
    CUADRADO, MA
    RICHARD, C
    ORTIZ, JM
    MARTINPEREZ, J
    LEON, J
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1995, 215 (03) : 889 - 895
  • [5] Histone deacetylase inhibitor, Trichostatin A, activates p21WAF1/CIP1 expression through downregulation of c-myc and release of the repression of c-myc from the promoter in human cervical cancer cells
    Li, H
    Wu, XX
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2004, 324 (02) : 860 - 867
  • [6] Aggressive tumor growth of human TUR leukemia cells is associated with high levels of c-myc expression and down-regulation of p20-max
    Hass, R
    LopezGuerrero, JA
    INTERNATIONAL JOURNAL OF CANCER, 1997, 72 (06) : 1113 - 1116
  • [7] Oridonin induces apoptosis and senescence in colorectal cancer cells by increasing histone hyperacetylation and regulation of p16, p21, p27 and c-myc
    Feng-Hou Gao
    Xiao-Hui Hu
    Wei Li
    Hua Liu
    Yan-Jie Zhang
    Zhu-Ying Guo
    Mang-Hua Xu
    Shi-Ting Wang
    Bin Jiang
    Feng Liu
    Ying-Zheng Zhao
    Yong Fang
    Fang-Yuan Chen
    Ying-Li Wu
    BMC Cancer, 10
  • [8] Oridonin induces apoptosis and senescence in colorectal cancer cells by increasing histone hyperacetylation and regulation of p16, p21, p27 and c-myc
    Gao, Feng-Hou
    Hu, Xiao-Hui
    Li, Wei
    Liu, Hua
    Zhang, Yan-Jie
    Guo, Zhu-Ying
    Xu, Mang-Hua
    Wang, Shi-Ting
    Jiang, Bin
    Liu, Feng
    Zhao, Ying-Zheng
    Fang, Yong
    Chen, Fang-Yuan
    Wu, Ying-Li
    BMC CANCER, 2010, 10
  • [9] Inhibition of c-Myc down-regulation by sustained ERK activation prevents methotrexate induced differentiation in A549 human lung adenocarcinoma cells
    Alemany, R.
    Voegel, O.
    Gutierrez, A.
    Navarro, M.
    Ros, T.
    Saus, C.
    Gines, J.
    Sampol, A.
    Amat, J. C.
    Martin, J.
    Galmes, A.
    Besalduch, J.
    Serra, J. M.
    FUNDAMENTAL & CLINICAL PHARMACOLOGY, 2008, 22 : 94 - 94
  • [10] The Histone Deacetylase Inhibitor Trichostatin A Sensitizes Human Renal Carcinoma Cells to TRAIL-Induced Apoptosis through Down-Regulation of c-FLIPL
    Han, Min Ho
    Park, Cheol
    Kwon, Taek Kyu
    Kim, Gi-Young
    Kim, Wun-Jae
    Hong, Sang Hoon
    Yoo, Young Hyun
    Choi, Yung Hyun
    BIOMOLECULES & THERAPEUTICS, 2015, 23 (01) : 31 - 38
123