Facile synthesis of highly functionalized N-methyl amino acid esters without side-chain protection

被引：52
|
作者：
White, KN [1 ]
Konopelski, JP [1 ]
机构：
[1] Univ Calif Santa Cruz, Dept Chem & Biochem, Santa Cruz, CA 95064 USA
来源：
ORGANIC LETTERS | 2005年 / 7卷 / 19期
关键词：
D O I：
10.1021/ol051441w
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The facile, two-pot synthesis of N-methyl amino acid esters by way of reductive amination is presented. Side chain protection schemes are not required, the starting materials are all commercially available, and the synthetic method is straightforward and affords desired product in very high yield.
引用
收藏
页码：4111 / 4112
页数：2
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