Excipients Used for Modified Nasal Drug Delivery: A Mini-Review of the Recent Advances

被引：9
|
作者：
Protopapa, Chrystalla [1 ]
Siamidi, Angeliki [1 ]
Pavlou, Panagoula [2 ]
Vlachou, Marilena [1 ]
机构：
[1] Natl & Kapodistrian Univ Athens, Sch Hlth Sci, Dept Pharm, Sect Pharmaceut Technol, Athens 15784, Greece
[2] Univ West Attica, Dept Biomed Sci, Div Aesthet & Cosmet Sci, 28 Ag Spyridonos Str, Egaleo 12243, Greece
来源：
MATERIALS | 2022年 / 15卷 / 19期
关键词：
nasal drug delivery; poloxamer; chitosan; gellan gum; vaccines; excipients; nanoparticles; LINKED DEXTRAN MICROSPHERES; DRY POWDER FORMULATION; BRAIN DELIVERY; IN-VITRO; MUCOCILIARY CLEARANCE; CHITOSAN NANOSPHERES; INTRANASAL DELIVERY; OLFACTORY REGION; INFLUENZA-VIRUS; NANOPARTICLES;
D O I：
10.3390/ma15196547
中图分类号：
O64 [物理化学（理论化学）、化学物理学];
学科分类号：
070304 ; 081704 ;
摘要：
The ongoing challenging task in the field of nasal drug delivery is the maintenance of an efficient concentration of the active substance in the target area for an adequate period of time. Thus, there is an urgent need to develop effective new strategies for drug delivery to the nose, using cutting edge technology and materials for this particular type of drug delivery. This review gives an account of the critical components of nasal drug delivery and the parameters influencing drug absorption in the nose, including the excipients required for modified drug administration.
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收藏
页数：15
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