Breaking the Enigma Code of Angiotensin II Type 2 Receptor Signaling

被引：6

作者：

Sadybekov, Anastasiia ^{[1
]}

Katritch, Vsevolod ^{[1
,2
]}

机构：

[1] Univ Southern Calif, Dept Chem, Bridge Inst, Los Angeles, CA 90089 USA

[2] Univ Southern Calif, Dept Quantitat & Computat Biol, Bridge Inst, Los Angeles, CA 90089 USA

来源：

STRUCTURE | 2020年 / 28卷 / 04期

关键词：

D O I：

10.1016/j.str.2020.03.004

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

In this issue of Structure, Asada et al. (2019) present angiotensin receptor AT2R structure in complex with its main endogenous agonist, AngII peptide. Complementing the previous structural studies, the new complex structure sheds light on the AT2R activation mechanism and opens new avenues for drug discovery targeting this enigmatic receptor.

引用

页码：390 / 392

页数：3

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