Generation of isogenic pluripotent stem cells

被引：23
|
作者：
Byrne, James A. [1 ]
机构：
[1] Stanford Univ, Sch Med, Inst Stem Cell Biol & Regenerat Med, Dept Obstet & Gynecol,Ctr Human Embryon Stem Cell, Palo Alto, CA 94304 USA
来源：
HUMAN MOLECULAR GENETICS | 2008年 / 17卷
关键词：
D O I：
10.1093/hmg/ddn053
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
The ability to reprogram somatic cell nuclei back into a pluripotent epigenetic state provides exciting new possibilities for in vitro research and cell transplantation therapy. There has been a significant quantity of recent research studies demonstrating that this epigenetic reprogramming process is possible with human and non-human primate somatic cells. In this review, various methodologies for reprogramming primate somatic cells into pluripotent stem cells are examined, epigenetic reprogramming following somatic cell nuclear transfer and normal primate embryonic development is compared, and future potential methods to induce direct reprogramming without using genetic modification are discussed.
引用
收藏
页码：R37 / R41
页数：5
相关论文
共 50 条
  • [1] Generation of Isogenic Pairs of Mutant and Complemented Fanconi Anemia Human Induced Pluripotent Stem Cells
    Marquez, Laura I.
    Schubert, Kathryn
    Galivo, Feorillo
    Finegold, Milton
    Olson, Susan
    Grompe, Markus
    MOLECULAR THERAPY, 2013, 21 : S179 - S179
  • [2] Modeling Choroideremia Disease with Isogenic Induced Pluripotent Stem Cells
    Fonseca, Ana Fragoso
    Coelho, Rita
    Lopes-da-Silva, Mafalda
    Lemos, Luisa
    Hall, Michael J.
    Oliveira, Daniela
    Falcao, Ana Sofia
    Tenreiro, Sandra
    Seabra, Miguel C.
    Antas, Pedro
    STEM CELLS AND DEVELOPMENT, 2024, 33 (19-20) : 528 - 539
  • [3] Modeling Chromosome Hemizygosity in Isogenic Human Pluripotent Stem Cells
    Kotini, Andriana G.
    Boussaad, Ibrahim
    Papapetrou, Eirini P.
    MOLECULAR THERAPY, 2014, 22 : S13 - S13
  • [4] Generation of integration-free Down syndrome and isogenic euploid human induced pluripotent stem cells
    Nehra, Sunita
    Sharma, Vishi
    Umrani, Malati
    Singhal, Nishant
    STEM CELL RESEARCH, 2023, 67
  • [5] Generation of Isogenic Pluripotent Stem Cells Differing Exclusively at Two Early Onset Parkinson Point Mutations
    Soldner, Frank
    Laganiere, Josee
    Cheng, Albert W.
    Hockemeyer, Dirk
    Gao, Qing
    Alagappan, Raaji
    Khurana, Vikram
    Golbe, Lawrence I.
    Myers, Richard H.
    Lindquist, Susan
    Zhang, Lei
    Guschin, Dmitry
    Fong, Lauren K.
    Vu, B. Joseph
    Meng, Xiangdong
    Urnov, Fyodor D.
    Rebar, Edward J.
    Gregory, Philip D.
    Zhang, H. Steve
    Jaenisch, Rudolf
    CELL, 2011, 146 (02) : 318 - 331
  • [6] Generation of an Isogenic Hereditary Hemorrhagic Telangiectasia Model via Prime Editing in Human Induced Pluripotent Stem Cells
    Kim, Min Woo
    Jeong, Kyu Sik
    Kim, Jin
    Lee, Seul-Gi
    Kim, C-Yoon
    Chung, Hyung Min
    INTERNATIONAL JOURNAL OF STEM CELLS, 2024,
  • [7] Highly efficient generation of isogenic pluripotent stem cell models using prime editing
    Li, Hanqin
    Busquets, Oriol
    Verma, Yogendra
    Syed, Khaja Mohieddin
    Kutnowski, Nitzan
    Pangilinan, Gabriella R.
    Gilbert, Luke A.
    Bateup, Helen S.
    Rio, Donald C.
    Hockemeyer, Dirk
    Soldner, Frank
    ELIFE, 2022, 11
  • [8] Generation of Human Isogenic Induced Pluripotent Stem Cell Lines with CRISPR Prime Editing
    Bonnycastle, Lori L.
    Swift, Amy J.
    Mansell, Erin C.
    Lee, Angela
    Winnicki, Elizabeth
    Li, Elizabeth S.
    Robertson, Catherine C.
    Parsons, Victoria A.
    Huynh, Trung
    Krilow, Chad
    Mohlke, Karen L.
    Erdos, Michael R.
    Narisu, Narisu
    Collins, Francis S.
    CRISPR JOURNAL, 2024, 7 (01): : 53 - 67
  • [9] Genomic Editing Tools to Model Human Diseases with Isogenic Pluripotent Stem Cells
    Kim, Huen Suk
    Bernitz, Jeffrey M.
    Lee, Dung-Fang
    Lemischka, Ihor R.
    STEM CELLS AND DEVELOPMENT, 2014, 23 (22) : 2673 - 2686
  • [10] Modeling sex differences in humans using isogenic induced pluripotent stem cells
    Waldhorn, Ithai
    Turetsky, Tikva
    Steiner, Debora
    Gil, Yaniv
    Benyamini, Hadar
    Gropp, Michal
    Reubinoff, Benjamin E.
    STEM CELL REPORTS, 2022, 17 (12): : 2732 - 2744
12345