A RANDOMIZED CONTROLLED TRIAL OF COGNITIVE-BEHAVIORAL THERAPY VERSUS TREATMENT AS USUAL FOR ADOLESCENTS WITH AUTISM SPECTRUM DISORDERS AND COMORBID ANXIETY

被引:91
|
作者
Storch, Eric A. [1 ,2 ,3 ,4 ]
Lewin, Adam B. [1 ,2 ]
Collier, Amanda B. [1 ]
Arnold, Elysse [1 ]
De Nadai, Alessandro S. [1 ,5 ]
Dane, Brittney F. [1 ]
Nadeau, Joshua M. [1 ,3 ]
Mutch, P. Jane [1 ]
Murphy, Tanya K. [1 ,2 ,4 ]
机构
[1] Univ S Florida, Dept Pediat, St Petersburg, FL 33701 USA
[2] Univ S Florida, Dept Psychiat & Behav Neurosci, St Petersburg, FL 33701 USA
[3] Rogers Behav Hlth, Tampa Bay, FL USA
[4] Univ S Florida, All Childrens Hosp, Johns Hopkins Med, St Petersburg, FL 33701 USA
[5] Univ S Florida, Dept Hlth Policy & Management, Tampa, FL USA
关键词
autism spectrum disorder; anxiety; adolescents; cognitive-behavioral therapy; obsessive-compulsive disorder; OBSESSIVE-COMPULSIVE DISORDER; QUALITY-OF-LIFE; RATING-SCALE; CHILDHOOD AUTISM; SOCIAL ANXIETY; CHILDREN; YOUTH; INTERVENTION; RELIABILITY; IMPAIRMENT;
D O I
10.1002/da.22332
中图分类号
B849 [应用心理学];
学科分类号
040203 ;
摘要
ObjectiveExamine the efficacy of a personalized, modular cognitive-behavioral therapy (CBT) protocol among early adolescents with high-functioning autism spectrum disorders (ASDs) and co-occurring anxiety relative to treatment as usual (TAU). MethodThirty-one children (11-16 years) with ASD and clinically significant anxiety were randomly assigned to receive 16 weekly CBT sessions or an equivalent duration of TAU. Participants were assessed by blinded raters at screening, posttreatment, and 1-month follow-up. ResultsYouth randomized to CBT demonstrated superior improvement across primary outcomes relative to those receiving TAU. Eleven of 16 adolescents randomized to CBT were treatment responders, versus 4 of 15 in the TAU condition. Gains were maintained at 1-month follow-up for CBT responders. ConclusionsThese data extend findings of the promising effects of CBT in anxious youth with ASD to early adolescents.
引用
收藏
页码:174 / 181
页数:8
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