PBI-4050 reduces liver damage and fibrosis in a high-fat diet mouse model of obesity and metabolic syndrome

被引:0
|
作者
Grouix, B. [1 ]
Sarra-Bournet, F. [1 ]
Tremblay, M. [1 ]
Felton, A. [1 ]
Laurin, P. [1 ]
Gagnon, L. [1 ]
机构
[1] ProMet BioSci Inc, Laval, PQ, Canada
关键词
D O I
10.1016/S0168-8278(17)30607-4
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
THU-376
引用
收藏
页码:S165 / S165
页数:1
相关论文
共 50 条
  • [1] PBI-4050 Reduces Liver Damage in a High-Fat Diet Mouse Model of Obesity and Metabolic Syndrome
    Grouix, Brigitte
    Sarra-Bournet, Francois
    Tremblay, Mikael
    Felton, Alexandra
    Laurin, Pierre
    Gagnon, Lyne
    HEPATOLOGY, 2017, 66 : 1066A - 1067A
  • [2] PBI-4050 restores liver and adipose tissue metabolic homeostasis, and decreases fibrosis in a high-fat-diet mouse model of nonalcoholic fatty liver disease
    Grouix, Brigitte
    Simard, Jean-Christophe
    Thibodeau, Jean-Francois
    Tremblay, Mikael
    Laverdure, Alexandre
    Sarra-Bournet, Francois
    Corpuz, Ramon
    Gagnon, Lyne
    JOURNAL OF HEPATOLOGY, 2020, 73 : S656 - S657
  • [3] PBI-4547 Improves Glucose Metabolism and Insulin Resistance, and Reduces Liver Damage in a High-Fat Diet Mouse Model of Obesity and Metabolic Syndrome
    Leduc, Martin
    Grouix, Brigitte
    Tremblay, Mikael
    Gervais, Liette
    Sarra-Bournet, Francois
    Felton, Alexandra
    Simard, Jean-Christophe
    Leblond, Francois A.
    Laurin, Pierre
    Gagnon, Lyne
    DIABETES, 2018, 67
  • [4] PBI-4050 REVERSES METABOLIC DYSREGULATION INDUCED BY A HIGH FAT DIET IN A MOUSE MODEL OF NON-ALCOHOLIC FATTY LIVER DISEASE
    Grouix, Brigitte
    Tremblay, Mikael
    Simard, Jean-Christophe
    Laverdure, Alexandre
    Corpuz, Ramon
    Leblond, Francois A.
    Leduc, Martin
    HEPATOLOGY, 2019, 70 : 1265A - 1265A
  • [5] Improves Glucose Metabolism and Insulin Resistance, and Reduces Liver Damage in a High-Fat Diet Mouse Model of Obesity and Metabolic Syndrome
    Grouix, Brigitte
    Tremblay, Mikael
    Gervais, Liette
    Sarrabournet, Francois
    Felton, Alexandra
    Laurin, Pierre
    Gagnon, Lyne
    DIABETES, 2017, 66 : A540 - A540
  • [6] PBI-4050 Reduces Cardiovascular Biomarkers in Type II Diabetic Patients With Metabolic Syndrome
    Laurin, Pierre
    Grouix, Brigitte
    Laverdure, Alexandre
    Zacharie, Boulos
    Gagnon, Lyne
    CIRCULATION, 2016, 134
  • [7] ACE Reduces Metabolic Abnormalities in a High-Fat Diet Mouse Model
    Lee, Seong-Jong
    Han, Jong-Min
    Lee, Jin-Seok
    Son, Chang-Gue
    Im, Hwi-Jin
    Jo, Hyun-Kyung
    Yoo, Ho-Ryong
    Kim, Yoon-Sik
    Seol, In-Chan
    EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE, 2015, 2015
  • [8] PBI-4050 Protects against Diabetic Nephropathy and Improves Pancreatic Function in High-Fat-Diet db/db Mouse Model
    Gagnon, Lyne
    Cloutier, Marie-Pier
    Tremblay, Mikael
    Gervais, Liette
    Sarra-Bournet, Francois
    Felton, Alexandra
    Hince, Kathy
    Laurin, Pierre
    Grouix, Brigitte
    DIABETES, 2017, 66 : A14 - A14
  • [9] Liver Glycogen Reduces Food Intake and Attenuates Obesity in a High-Fat Diet-Fed Mouse Model
    Lopez-Soldado, Iliana
    Zafra, Delia
    Duran, Jordi
    Adrover, Anna
    Calbo, Joaquim
    Guinovart, Joan J.
    DIABETES, 2015, 64 (03) : 796 - 807
  • [10] PBI-4050 Reduces Key Cardiorenal Biomarkers and Urinary Microparticles in Type 2 Diabetes Patients with Metabolic Syndrome
    Laurin, Pierre
    Moran, John
    Senior, Peter A.
    Grouix, Brigitte
    Hagerimana, Aline
    Dorion, Catherine
    Gervais, Liette
    Laverdure, Alexandre
    Hince, Kathy
    Geerts, Lilianne
    Sarra-Bournet, Francois
    Felton, Alexandra
    Gagnon, William
    Leduc, Martin
    Tremblay, Mikael
    Cloutier, Mariepier
    Zacharie, Boulos
    Duceppe, Jean-Simon
    Abbott, Shaun
    Cesari, Frank
    Gagnon, Lyne
    DIABETES, 2017, 66 : A310 - A310