Application of titanium dioxide (TiO2) nanoparticles in cancer therapies

被引:140
|
作者
Cesmeli, Selin [1 ]
Avci, Cigir Biray [1 ]
机构
[1] Ege Univ, Tip Fak, Izmir, Turkey
关键词
Nanoparticles; cancer; photodynamic therapy; sonodynamic therapy; titanium dioxide;
D O I
10.1080/1061186X.2018.1527338
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
Cancer is one of the most common diseases all over the world; many people suffer from diverse types of cancer. However, currently there is no exact cure or therapy developed for cancer. On the other hand, nanoparticles are defined as microscopic particles that have dimensions less than 100 nm and they are known for their usage in health sciences and medicine, however a few harmful effects on different animal cells. Therefore, researchers began to use nanoparticles for cancer therapies and to develop new methods for much more effective therapies. Nanoparticles in cancer studies are commonly used in photodynamic therapy (PDT) and sonodynamic therapy (SDT) as a sensitising agent, in computed tomography imaging (CT) and radiation therapy as an enhancement agent, in dual-mode image contrast and enhancement therapy as an image contrast agent. Titanium dioxide nanoparticles (TiO2 NPs) are known as commonly used nanoparticles in medical applications and hence in cancer studies. They are used in PDT, SDT and drug delivery systems. As cancer continues to affect people, new therapeutics and therapies will be developed and nanotechnology for this aim will be an important approach for the researchers.
引用
收藏
页码:762 / 766
页数:5
相关论文
共 50 条
  • [1] The application of titanium dioxide (TiO2) nanoparticles in the photo-thermal therapy of melanoma cancer model
    Behnam, Mohammad Ali
    Emami, Farzin
    Sobhani, Zahra
    Dehghanian, Amir Reza
    [J]. IRANIAN JOURNAL OF BASIC MEDICAL SCIENCES, 2018, 21 (11) : 1133 - 1139
  • [2] Electrospray Deposition Of Titanium Dioxide (TiO2) Nanoparticles
    Halimi, Siti Umairah
    Abu Bakar, Noor Fitrah
    Ismail, Siti Norazian
    Hashib, Syafiza Abd
    Naim, M. Nazli
    [J]. 5TH NANOSCIENCE AND NANOTECHNOLOGY SYMPOSIUM (NNS2013), 2014, 1586 : 57 - 62
  • [3] Synthesis and Characterization of Titanium dioxide (TiO2) Nanoparticles
    Srikanth, R.
    Rao, H. Joga
    [J]. RESEARCH JOURNAL OF PHARMACEUTICAL BIOLOGICAL AND CHEMICAL SCIENCES, 2018, 9 (04): : 313 - 319
  • [4] Application of Titanium Dioxide (TiO2) Nanoparticles in Photodynamic Therapy (PDT) of an Experimental Tumor
    Miyoshi, Norio
    Kume, Kyo
    Tsutumi, Kotaro
    Fukunaga, Yukihiro
    Ito, Shinnji
    Imamura, Yoshiaki
    Bibin, Andriana B.
    [J]. 4TH NANOSCIENCE AND NANOTECHNOLOGY SYMPOSIUM (NNS2011): AN INTERNATIONAL SYMPOSIUM, 2011, 1415
  • [5] Activation of human neutrophils by titanium dioxide (TiO2) nanoparticles
    Goncalves, D. M.
    Chiasson, S.
    Girard, D.
    [J]. TOXICOLOGY IN VITRO, 2010, 24 (03) : 1002 - 1008
  • [6] Titanium Dioxide Nanoparticles (TiO2) Quenching Based Aptasensing Platform: Application to Ochratoxin A Detection
    Sharma, Atul
    Hayat, Akhtar
    Mishra, Rupesh K.
    Catanante, Gaelle
    Bhand, Sunil
    Marty, Jean Louis
    [J]. TOXINS, 2015, 7 (09): : 3771 - 3784
  • [7] Toxicology of Titanium Dioxide (TiO2) Nanoparticles: In vitro and in vivo evaluation of macrophage uptake of TiO2
    Miller, Terry J.
    Knapton, Alan
    Adeyemo, Oluwafunke
    Noory, Laila S.
    Weaver, James L.
    Hanig, Joseph P.
    Honchel, Ronald
    Zhang, Jun
    Espandiari, Parvaneh
    Benedick, Matthew F.
    Umbreit, Thomas H.
    Tomazic-Jezic, Vesna J.
    Sadrieh, Nakissa
    [J]. FASEB JOURNAL, 2007, 21 (06): : A812 - A812
  • [8] Toxicokinetics of titanium dioxide (TiO2) nanoparticles after inhalation in rats
    Pujalte, Igor
    Dieme, Denis
    Haddad, Sami
    Serventi, Alessandra Maria
    Bouchard, Michele
    [J]. TOXICOLOGY LETTERS, 2017, 265 : 77 - 85
  • [9] Titanium dioxide (TiO2) fundamentals
    Lashway, WH
    [J]. TAPPI POLYMERS, LAMINATIONS & COATINGS CONFERENCE, VOLS 1 AND 2, 1999, : 97 - 140
  • [10] The application of titanium dioxide (TiO2) in aqueous system: A short review
    Yan, Evyan Yang Chia
    Yoke, Chong Mee
    Chin-Hua, Chia
    Zakaria, Sarani
    [J]. PROCEEDINGS OF MECHANICAL ENGINEERING RESEARCH DAY 2020 (MERD'20), 2020, : 118 - 120