Spatially encoded polarization-dependent nonlinear optics

被引：2
|
作者：
Ulcickas, James R. W. [1 ]
Ding, Changqin [1 ]
Deng, Fengyuan [1 ]
Simpson, Garth J. [1 ]
机构：
[1] Purdue Univ, Dept Chem, W Lafayette, IN 47907 USA
来源：
OPTICS LETTERS | 2018年 / 43卷 / 24期
基金：
美国国家科学基金会; 美国国家卫生研究院;
关键词：
2ND-HARMONIC GENERATION; COLLAGEN;
D O I：
10.1364/OL.43.005973
中图分类号：
O43 [光学];
学科分类号：
070207 ; 0803 ;
摘要：
A single fixed optic is combined with the sample translation capabilities inherent to most microscopes to achieve precise polarization-dependent second harmonic generation microscopy measurements of thin tissue sections. Although polarization measurements have enabled detailed structural analysis of collagen, challenges in integrating rotation stages or fast electro-optic/photoelastic modulation have complicated the retrofitting of existing systems for precise polarization analysis. Placing a static microretarder array in the rear conjugate plane resulted in spatially encoded polarization modulation across the field of view. A complete set of polarization rotation measurements was acquired at each pixel by sample translation, recovering local-frame tensors relating to structure within collagenous tissue. (c) 2018 Optical Society of America
引用
收藏
页码：5973 / 5976
页数：4
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