A Polytetrafluoroethylene (PTFE) and Nano-Al2O3 Based Composite Coating with a Bacteriostatic Effect against E. coli and Low Cytotoxicity

被引:8
|
作者
Burmistrov, Dmitriy E. [1 ]
Serov, Dmitriy A. [1 ]
Simakin, Aleksander, V [1 ]
Baimler, Ilya, V [1 ]
Uvarov, Oleg, V [1 ]
Gudkov, Sergey, V [1 ]
机构
[1] Russian Acad Sci, Prokhorov Gen Phys Inst, 38 Vavilova St, Moscow 119991, Russia
关键词
aluminum oxide; polytetrafluoroethylene (PTFE); nanoparticles; composite; biocompatibility; antibacterial coating; cytotoxicity; COPPER-OXIDE NANOPARTICLES; ANTIBACTERIAL ACTIVITY; ANTIMICROBIAL PROPERTIES; AL2O3; NANOPARTICLES; BIOFILMS; DAMAGE; LASER; 8-OXOGUANINE; IRRADIATION; PERFORMANCE;
D O I
10.3390/polym14214764
中图分类号
O63 [高分子化学(高聚物)];
学科分类号
070305 ; 080501 ; 081704 ;
摘要
The problem of bacterial contamination through surfaces is important for the food industry. In this regard, there is a growing interest in new coatings based on nanoparticles that can provide a long-term antibacterial effect. Aluminum oxide nanoparticles are a good candidate for such coatings due to their availability and good biocompatibility. In this study, a coating containing aluminum oxide nanoparticles was produced using polytetrafluoroethylene as a polymer matrix-a polymer that exhibits excellent mechanical and physicochemical properties and it is not toxic. The obtained coatings based on "liquid Teflon" containing various concentrations of nanoparticles (0.001-0.1 wt%) prevented the bacterial growth, and they did not exhibit a cytotoxicity on animal cells in vitro. Such coatings are designed not only to provide an antibacterial surface effect, but also to eliminate micro damages on surfaces that inevitably occur in the process of food production.
引用
收藏
页数:16
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