Tetracyclic Triterpenoids in Herbal Medicines and their Activities in Diabetes and its Complications

被引：23
|
作者：
Hamid, Kaiser [1 ]
Alqahtani, Ali [1 ]
Kim, Moon-Sun [1 ]
Cho, Jun-Lae [1 ]
Cui, Pei H. [1 ]
Li, Chun Guang [2 ]
Groundwater, Paul W. [1 ]
Li, George Q. [1 ]
机构：
[1] Univ Sydney, Fac Pharm, Sydney, NSW 2006, Australia
[2] Univ Western Sydney, Natl Inst Complementary Med, Sydney, NSW 2006, Australia
来源：
CURRENT TOPICS IN MEDICINAL CHEMISTRY | 2015年 / 15卷 / 23期
关键词：
Astragalus; diabetes; Diabetic complications; Ginseng; Gynostemma; Herbal medicines; Tetracyclic triterpenoids; ACTIVATED PROTEIN-KINASE; STIMULATES GLUCOSE-UPTAKE; TYROSINE-PHOSPHATASE; 1B; KOREAN RED GINSENG; PERFORMANCE LIQUID-CHROMATOGRAPHY; GLOMERULAR-FILTRATION-RATE; CHARANTIA WILD VARIANT; CELL-CYCLE ARREST; GANODERIC ACID T; HIGH-FAT DIET;
D O I：
10.2174/1568026615666150619141940
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
Tetracyclic triterpenoids, including the dammarane, cucurbitane, cycloartane, lanostane and protostane groups, is a class of triterpenoids widely distributed in various medicinal plants, particularly those commonly used for the treatment of diabetes and its complications, such as Panax ginseng, Panax quinquefolium, Panax notoginseng, Gynostemma pentaphyllum, Astragalus membranaceus, Momordica charantia, and Ganoderma lucidum. This review highlights recent findings on the chemistry and bioactivities of tetracyclic triterpenoids from these plants and other popular herbal medicines.
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收藏
页码：2406 / 2430
页数：25
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