Evidence of Vaccine-related Reassortment of Rotavirus, Brazil, 2008-2010

被引:28
|
作者
Rose, Tatiana Lundgren [1 ]
Marques da Silva, Marcelle Figueira [1 ]
Gomez, Mariela Martinez [1 ]
Resque, Hugo Reis [1 ]
Travassos Ichihara, Maria Yury [2 ]
Volotao, Eduardo de Mello [1 ]
Gagliardi Leite, Jose Paulo [1 ]
机构
[1] Inst Oswaldo Cruz, BR-20001 Rio De Janeiro, Brazil
[2] Univ Fed Bahia, Salvador, BA, Brazil
关键词
VP7;
D O I
10.3201/eid1911.121407
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Analysis of 27 rotavirus strains from vaccinated and unvaccinated children revealed reassortment events in 3 strains: a gene derived from a vaccine; a gene acquired from a circulating strain; and reassortment between circulating strains. Data suggest that the widespread use of this monovalent rotavirus vaccine may introduce vaccine genes into circulating human rotaviruses or vice versa.
引用
收藏
页码:1843 / 1846
页数:4
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