Two new cytotoxic sesquiterpenoids from Solanum lyratum

被引：12
|
作者：
Li, Gui-Sheng [1 ]
Yao, Fang [1 ]
Zhang, Lei [1 ]
Yue, Xi-Dian [1 ]
Dai, Sheng-Jun [1 ]
机构：
[1] Yantai Univ, Sch Pharmaceut Sci, Yantai 264005, Peoples R China
来源：
CHINESE CHEMICAL LETTERS | 2013年 / 24卷 / 11期
关键词：
Solanum lyratum; Solanaceae; Sesquiterpenoid; Solajiangxins F-G; Cytotoxic activity;
D O I：
10.1016/j.cclet.2013.07.025
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Two new sesquiterpenoids, attributable to eudesmane-type (1 and 2, named solajiangxins F and G), were isolated from the whole plant of Solanum lyratum. Their structures were elucidated on the basis of integrated spectroscopic techniques. In vitro, compounds 1 and 2 were found to show significant cytotoxic activity against selected cancer cells, including P-388, HONE-1 and HT-29. (C) 2013 Sheng-Jun Dai. Published by Elsevier B.V. on behalf of Chinese Chemical Society. All rights reserved.
引用
收藏
页码：1030 / 1032
页数：3
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