Severe obstetric bleeding treated with recombinant activated factor VII (rFVIIa)

被引:0
|
作者
Segal, S [1 ]
Shemesh, IY [1 ]
Blumental, R [1 ]
Yoffe, B [1 ]
Laufer, N [1 ]
Ezra, Y [1 ]
Levy, I [1 ]
Mazor, M [1 ]
Martinowitz, U [1 ]
机构
[1] Chaim Sheba Med Ctr, Dept Obstet & Gynecol, IL-52621 Tel Hashomer, Israel
关键词
D O I
暂无
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
Recombinant activated factor VII (rFVIIa; NovoSeven(R)) was successfully used in 3 patients with massive obstetric hemorrhage caused by placenta previa accreta, rupture of the uterine wall and preeclampsia complicated by HELLP syndrome. rFVIIa was administered intravenously to the 3 patients after all hemostatic attempts failed, they were critically ill multi-transfused and close to exsanguination. In one patient this treatment was life-saving and in the other two it helped to control the bleeding. rFVIIa is a promising new agent for hemorrhage control in massive obstetric bleeding.
引用
收藏
页码:43 / 46
页数:4
相关论文
共 50 条
  • [1] Treatment of obstetric hemorrhage with recombinant activated factor VII (rFVIIa)
    S. Segal
    I. Y. Shemesh
    R. Blumenthal
    B. Yoffe
    N. Laufer
    Y. Ezra
    I. Levy
    M. Mazor
    U. Martinowitz
    [J]. Archives of Gynecology and Obstetrics, 2003, 268 (4) : 266 - 267
  • [2] Control of a persistent obstetric haemorrhage with activated recombinant factor VII (rFVIIA)
    Jakobsen, DJ
    Shemesh, IY
    Boksenbojm, PM
    Blumenntal, R
    Segal, S
    Yoffe, B
    Martinovitz, U
    [J]. INTENSIVE CARE MEDICINE, 2001, 27 : S173 - S173
  • [3] Activated recombinant factor VII (rFVIIa)
    Grottke, Oliver
    Henzler, Dietrich
    Rossaint, Rolf
    [J]. BEST PRACTICE & RESEARCH-CLINICAL ANAESTHESIOLOGY, 2010, 24 (01) : 95 - 106
  • [4] Recombinant activated factor VII (rFVIIa) in the treatment of 13 patients with severe and active bleeding esophageal varices
    Romero-Castro, R
    Pellicer-Bautista, F
    Jimenez-Saenz, M
    Gomez-Parra, M
    Sendon-Perez, A
    Guerrero-Aznar, MD
    Herrerias-Gutierrez, JM
    [J]. GASTROENTEROLOGY, 2004, 126 (04) : A386 - A386
  • [5] Recombinant activated factor VII (rFVIIa) in the treatment of seven cases of severe and active bleeding esophageal varices
    Romero, R
    Pellicer, F
    Jimenez, M
    Gomez, M
    Guerrero, MD
    Sendon, A
    Herrerias, JM
    [J]. GASTROINTESTINAL ENDOSCOPY, 2003, 57 (05) : AB143 - AB143
  • [6] Recombinant activated factor VII in the management of massive obstetric bleeding
    Palomino, MAP
    Chaparro, MJS
    De Elvira, MJZR
    Curiel, EB
    [J]. BLOOD COAGULATION & FIBRINOLYSIS, 2006, 17 (03) : 226 - 227
  • [7] Pharmacokinetics of recombinant activated factor VII (rFVIIa)
    Erhardtsen, E
    [J]. SEMINARS IN THROMBOSIS AND HEMOSTASIS, 2000, 26 (04): : 385 - 391
  • [8] Hemostasis in severe postpartum hemorrhage - The effect of recombinant activated factor VII (RFVIIA)
    Segal, S
    Shemesh, IY
    Yoffe, B
    Laufer, N
    Mankuta, D
    Mazor, M
    Zohar, S
    Shiff, E
    Ben-Tal, O
    Pauzner, D
    Martinowitz, U
    [J]. THROMBOSIS RESEARCH, 2005, 115 : 141 - 141
  • [9] Recombinant activated factor VII (rFVIIa) for the treatment of bleeding secondary to acquired factor VIII inhibitor
    Baudo, F
    Gaidano, G
    Carloni, MT
    Coppola, A
    Fariciotti, A
    Iorio, A
    Marietta, M
    Marongiu, F
    Mazzucconi, MG
    Miraglia, E
    Schiavoni, M
    Schinco, PC
    [J]. BLOOD, 2002, 100 (11) : 100B - 100B
  • [10] Use of recombinant activated factor VII (rFVIIa) in pediatric patients with high bleeding risk
    Sciuccati, C.
    Hepner, M.
    Torres, A. Feliu
    Pieroni, G.
    Gomez, J. Avalos
    Bonduel, M.
    [J]. HAEMOPHILIA, 2010, 16 : 115 - 115